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[疥疮——对氯菊酯治疗的临床耐药性:病例报告及对当前治疗建议的批判性讨论]

[Scabies-clinical resistance to permethrin therapy : Case reports and a critical discussion of current treatment recommendations].

作者信息

Mang Renz, Kremer Almut, Lehmann Percy, Assmann Till

机构信息

Gemeinschaftspraxis für Dermatologie, Venerologie, Allergologie und Proktologie, Hautzentrum Wuppertal, Hauptstr. 36, 42349, Wuppertal, Deutschland.

Klinik für Dermatologie, Allergologie und Umweltmedizin, HELIOS Universitätsklinikum Wuppertal, Universität Witten-Herdecke, Heusnerstr. 40, 42283, Wuppertal, Deutschland.

出版信息

Hautarzt. 2021 Jul;72(7):595-599. doi: 10.1007/s00105-021-04783-8. Epub 2021 Mar 15.

Abstract

Scabies is a contagious disease with increasing frequency. This is confirmed by data from insurance companies as well as increased search queries on Google. There is a controversial discussion in the scientific literature whether the mite has become resistant to standard therapy with permethrin. One case report and a group of cases (N = 12) from a mother-child facility are described in the following demonstrating decreased effectiveness of permethrin therapy. Dermatoscopy can be helpful in diagnosis and in assessing effectiveness of therapy. Dermatoscopic criteria are shown and therapeutic concepts are critically discussed.

摘要

疥疮是一种发病率日益上升的传染病。保险公司的数据以及谷歌上搜索查询量的增加都证实了这一点。科学文献中存在关于疥螨是否已对氯菊酯标准疗法产生耐药性的争议性讨论。以下描述了一例病例报告以及一家母子保健机构的一组病例(N = 12),显示氯菊酯疗法的有效性降低。皮肤镜检查有助于诊断和评估治疗效果。展示了皮肤镜检查标准并对治疗理念进行了批判性讨论。

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