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可生物降解的花状锰用于协同光热和光动力治疗应用。

Biodegradable flower-like manganese for synergistic photothermal and photodynamic therapy applications.

机构信息

Institute of Mass Spectrometry, State Key Laboratory Base of Novel Functional Materials and Preparation Science, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, 315211, People's Republic of China.

Department of Microelectronic Science and Engineering, Ningbo University, Ningbo, 315211, People's Republic of China.

出版信息

Photochem Photobiol Sci. 2021 Jan;20(1):153-160. doi: 10.1007/s43630-020-00010-w. Epub 2021 Jan 20.

Abstract

A flower-like nanostructured MnO with near-infrared (NIR) light-triggered high photothermal conversion capability of 30% and reactive oxygen species (ROS) generation ability was successfully developed. Different from the reported MnO nanomaterials those were used in the nanomedicine field for only relieving tumor hypoxia and/or imaging, the flower-like MnO inherently acts as a competent agent for simultaneously enhanced photothermal and photodynamic therapy. A flower-like nanostructured MnO2 with near-infrared (NIR) light triggered high photothermal conversion capability of 30% and reactive oxygen species (ROS) generation ability was successfully developed.

摘要

一种具有近红外(NIR)光触发的高光热转换能力(30%)和活性氧(ROS)生成能力的花状纳米结构 MnO2 已被成功开发。与已报道的仅用于缓解肿瘤缺氧和/或成像的纳米医学领域的 MnO 纳米材料不同,花状 MnO2 本身就是一种增强光热和光动力治疗的有效试剂。

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