Tillis T N, Murray D L, Schmidt G J, Weiter J J
Eye Research Institute of Retina Foundation, Boston, Massachusetts 02114.
Invest Ophthalmol Vis Sci. 1988 Jun;29(6):988-91.
Preretinal oxygen measurements were made in pigmented rabbits under conditions of light and dark. The avascular rabbit retina was chosen to eliminate the effects of autoregulation by the retinal vasculature, thus more clearly defining the role of the photoreceptors on preretinal measurements of oxygen delivery from the choroid. Measurements were made 50-100 micron away from the retina using oxygen microelectrodes. An average preretinal oxygen value of 9.8 +/- 1.3 SE mm Hg (n = 12) was measured in room light under normoxic conditions. A change from light to dark conditions always resulted in a measured decrease in preretinal oxygen levels. During the first 30 min of dark adaptation, a 25.8% (+/- 5.5% SD) decrease was obtained. This oxygen decrease is reversible during sequential light adaptation, reaching plateau in approximately 15-20 min. These results indicate that the photoreceptors have a significant effect on choroidal oxygen transmission across the retina.
在明和暗条件下对有色家兔进行视网膜前氧测量。选择无血管的家兔视网膜以消除视网膜血管系统自动调节的影响，从而更清楚地确定光感受器在视网膜前脉络膜氧输送测量中的作用。使用氧微电极在距视网膜50 - 100微米处进行测量。在常氧条件下的室内光线下，测得视网膜前平均氧值为9.8±1.3 SE毫米汞柱（n = 12）。从明条件转变为暗条件总是导致测得的视网膜前氧水平下降。在暗适应的最初30分钟内，氧含量下降了25.8%（±5.5%标准差）。这种氧含量下降在随后的光适应过程中是可逆的，大约在15 - 20分钟内达到平稳状态。这些结果表明，光感受器对脉络膜氧透过视网膜有显著影响。
