体外心肺复苏术抢救儿童重度氯喹中毒 1 例报告
Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child - a case report.
机构信息
Paediatric Intensive Care, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.
Department of Cardiovascular Surgery, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
出版信息
Scand J Trauma Resusc Emerg Med. 2021 Mar 15;29(1):48. doi: 10.1186/s13049-021-00850-0.
Abstract
BACKGROUND
Chloroquine use has increased worldwide recently in the setting of experimental treatment for the novel coronavirus disease (Covid-19). Nevertheless, in case of chloroquine intoxication, it can be life threatening, with cardiac arrest, due to its cardiac toxicity.
CASE PRESENTATION
This case study reports on a 14-years-old girl who presented in cardiac arrest after an uncommon suicide attempt by ingesting 3 g of chloroquine. After 66 min of cardio-pulmonary resuscitation (CPR), extracorporeal cardiopulmonary resuscitation (ECPR) was initiated, allowing cardiac function to recover.
CONCLUSIONS
Chloroquine intoxication is a rare but serious condition due to its cardiac toxicity. Use of ECPR in this case of transient toxicity allowed a favorable evolution with little neurological impairment.
摘要
背景
最近，在新型冠状病毒病（Covid-19）的实验性治疗中，氯喹的使用在全球范围内有所增加。然而，在氯喹中毒的情况下，由于其心脏毒性，可能会有生命危险，导致心脏骤停。
病例介绍
本病例报告了一名 14 岁女孩的情况，她因摄入 3 克氯喹而试图自杀，且行为罕见，之后出现心脏骤停。心肺复苏 66 分钟后，开始进行体外心肺复苏（ECPR），使心脏功能得以恢复。
结论
氯喹中毒是一种罕见但严重的疾病，因为其具有心脏毒性。在这种短暂毒性的情况下使用 ECPR 可实现有利的演变，且神经损伤较小。
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