Zhang Hu, Chen Jie, Chen Chen
Department of General Surgery, Xintai City People's Hospital, Xintai, Shandong Province, China.
Department of Intensive Care Unit, Xintai City People's Hospital, Xintai, Shandong Province, China.
J Minim Access Surg. 2021 Apr-Jun;17(2):147-152. doi: 10.4103/jmas.JMAS_294_19.
The objective was to assess the efficacy and safety in treating gastric stromal tumours by laparoscopy combined with gastroscopy positioning surgery.
The randomised controlled trials (RCTs), which are about the efficacy and safety of laparoscopy combined with gastroscopy positioning surgery in treating gastric stromal tumours were searched from the PubMed (1998-1990-2018.6), Wanfang Data (1990-2018.6), China National Knowledge Infrastructure (1979-2018.6) and International Statistical Institute (1998-2018.6). The data were extracted from these trials, and the meta-analysis was made through from RevMan 5.3 software.
Six RCTs involving 451 patients were included in the study (227 patients in the laparoscopy combined with gastroscopy positioning group and 224 patients in laparoscopic surgery group). Compared with laparoscopic surgery group, this meta-analysis showed that laparoscopy combined with gastroscopy positioning group could shorten the post-operation hospital stay (P < 0.05) and reduce the intraoperative blood loss (P < 0.05). However, there was no significant difference in others between the two groups, such as operation time (P > 0.05), post-operative time of recovery of intestinal peristalsis (P > 0.05) and the total hospital stay (P > 0.05).
Compared with laparoscopic surgery group, the better total effect occurs in laparoscopy combined with gastroscopy positioning group for the treatment of gastric stromal tumours is better. Laparoscopy combined with gastroscopy positioning group for the gastric stromal tumours is acceptable.
目的是评估腹腔镜联合胃镜定位手术治疗胃间质瘤的疗效及安全性。
从PubMed(1998 - 1990 - 2018.6)、万方数据(1990 - 2018.6)、中国知网(1979 - 2018.6)及国际统计学会(1998 - 2018.6)检索关于腹腔镜联合胃镜定位手术治疗胃间质瘤疗效及安全性的随机对照试验(RCT)。从这些试验中提取数据,并通过RevMan 5.3软件进行荟萃分析。
本研究纳入6项RCT,共451例患者(腹腔镜联合胃镜定位组227例,腹腔镜手术组224例)。与腹腔镜手术组相比,本荟萃分析表明腹腔镜联合胃镜定位组可缩短术后住院时间(P < 0.05)并减少术中出血量(P < 0.05)。然而,两组在其他方面无显著差异,如手术时间(P > 0.05)、术后肠道蠕动恢复时间(P > 0.05)及总住院时间(P > 0.05)。
与腹腔镜手术组相比,腹腔镜联合胃镜定位组治疗胃间质瘤的总体效果更好。腹腔镜联合胃镜定位组治疗胃间质瘤是可接受的。