Suppr超能文献

辐射损伤唾液腺机制与治疗的研究进展。

Advances on mechanism and treatment of salivary gland in radiation injury.

机构信息

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2021 Feb 1;39(1):99-104. doi: 10.7518/hxkq.2021.01.015.

Abstract

Oral squamous cell carcinoma (OSCC) is the most frequent tumour in head and neck malignant. The current treatment is mainly based on surgery therapy, radiation therapy and chemical therapy. Meanwhile, there are many a defect in the treatment. For example, there are many defects in radiotherapy. Radioactive salivatitis is the most common. In addition, there are a series of changes such as dry mouth, oral mucositis, rampant dental caries, and radioactive osteomyelitis of jaw, which cause swallowing, chewing problems, and taste dysfunction. Currently, the research on radioactive salivatitis is progressing rapidly, but its mechanism is more complication. This paper review aims to summarize the research progress in this field.

摘要

口腔鳞状细胞癌(OSCC)是头颈部恶性肿瘤中最常见的肿瘤。目前的治疗主要基于手术治疗、放射治疗和化学治疗。同时,治疗方法存在许多缺陷。例如,放射治疗存在许多缺陷。放射性涎腺炎是最常见的。此外,还会出现一系列变化,如口干、口腔黏膜炎、猖獗性龋齿和放射性颌骨骨髓炎,从而导致吞咽、咀嚼问题和味觉功能障碍。目前,放射性涎腺炎的研究进展迅速,但发病机制更为复杂。本文旨在综述该领域的研究进展。

相似文献

1
Advances on mechanism and treatment of salivary gland in radiation injury.辐射损伤唾液腺机制与治疗的研究进展。
Hua Xi Kou Qiang Yi Xue Za Zhi. 2021 Feb 1;39(1):99-104. doi: 10.7518/hxkq.2021.01.015.
2
Xerostomia in head and neck malignancy.头颈部恶性肿瘤中的口干症。
Oral Oncol. 2010 Jun;46(6):460-3. doi: 10.1016/j.oraloncology.2010.03.008. Epub 2010 Apr 18.
5
Modification of the submandibular gland transfer procedure.下颌下腺转移手术的改良
Laryngoscope. 2016 Nov;126(11):2492-2496. doi: 10.1002/lary.26029. Epub 2016 May 12.
9
Xerostomia: diagnosis and management.口干症:诊断与治疗
Oncology (Williston Park). 1996 Mar;10(3 Suppl):7-11.

本文引用的文献

4
Aquaporin gene therapy corrects Sjögren's syndrome phenotype in mice.水通道蛋白基因疗法可纠正小鼠的干燥综合征表型。
Proc Natl Acad Sci U S A. 2016 May 17;113(20):5694-9. doi: 10.1073/pnas.1601992113. Epub 2016 May 2.
8
Botulinum Toxin Confers Radioprotection in Murine Salivary Glands.肉毒杆菌毒素对小鼠唾液腺具有辐射防护作用。
Int J Radiat Oncol Biol Phys. 2016 Apr 1;94(5):1190-7. doi: 10.1016/j.ijrobp.2015.12.371. Epub 2015 Dec 29.
9
Cancer statistics in China, 2015.《中国癌症统计数据 2015》
CA Cancer J Clin. 2016 Mar-Apr;66(2):115-32. doi: 10.3322/caac.21338. Epub 2016 Jan 25.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验