State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2021 Feb 1;39(1):99-104. doi: 10.7518/hxkq.2021.01.015.
Oral squamous cell carcinoma (OSCC) is the most frequent tumour in head and neck malignant. The current treatment is mainly based on surgery therapy, radiation therapy and chemical therapy. Meanwhile, there are many a defect in the treatment. For example, there are many defects in radiotherapy. Radioactive salivatitis is the most common. In addition, there are a series of changes such as dry mouth, oral mucositis, rampant dental caries, and radioactive osteomyelitis of jaw, which cause swallowing, chewing problems, and taste dysfunction. Currently, the research on radioactive salivatitis is progressing rapidly, but its mechanism is more complication. This paper review aims to summarize the research progress in this field.
口腔鳞状细胞癌(OSCC)是头颈部恶性肿瘤中最常见的肿瘤。目前的治疗主要基于手术治疗、放射治疗和化学治疗。同时,治疗方法存在许多缺陷。例如,放射治疗存在许多缺陷。放射性涎腺炎是最常见的。此外,还会出现一系列变化,如口干、口腔黏膜炎、猖獗性龋齿和放射性颌骨骨髓炎,从而导致吞咽、咀嚼问题和味觉功能障碍。目前,放射性涎腺炎的研究进展迅速,但发病机制更为复杂。本文旨在综述该领域的研究进展。