Sharpley Christopher F, Christie David R H, Bitsika Vicki
Brain-Behaviour Research Group, University of New England, Armidale, New South Wales, Australia.
Genesiscare, John Flynn Private Hospital, Tugun, Queensland, Australia.
Am J Mens Health. 2021 Mar-Apr;15(2):15579883211001201. doi: 10.1177/15579883211001201.
Men who suffer from prostate cancer (PCa) need to make important decisions regarding their treatment options. There is some evidence that these men may suffer from sleep difficulties due to their cancer or its diagnosis and treatment. Although sleep difficulties have been associated with cognitive depression in other samples of men, they have not been examined in PCa patients, despite the importance of decision-making for these men. This study was designed to investigate the association between sleep difficulties and cognitive depression in PCa patients. A sample of 96 PCa patients completed a background questionnaire, the Zung Self-Rating Depression Scale, and the Insomnia Severity Index. Comparison was made between sleep difficulty scores from before the patients received their diagnosis of PCa to the time of survey, allowing use of a "retrospective pretest" methodology. Just over 61% of the sample reported a deterioration in sleep quality, and this was significantly associated with cognitive depression ( = .346, = .007). At the specific symptom level, significantly contributed to the variance in (R change = .140, for change = 9.298, = .003). Sleeping difficulties, particularly falling asleep, are common and associated with depression-related to ability to think clearly in PCa patients. This has potentially adverse effects upon the ability of men with PCa to understand their treatment options and make decisions about them.
患有前列腺癌（PCa）的男性需要就其治疗方案做出重要决定。有证据表明，这些男性可能由于癌症或其诊断及治疗而存在睡眠困难。尽管在其他男性样本中，睡眠困难与认知性抑郁有关，但尽管决策对这些男性很重要，在前列腺癌患者中尚未对此进行研究。本研究旨在调查前列腺癌患者睡眠困难与认知性抑郁之间的关联。96名前列腺癌患者的样本完成了一份背景问卷、zung自评抑郁量表和失眠严重程度指数。对患者在被诊断为前列腺癌之前到调查时的睡眠困难评分进行了比较，从而可以使用“回顾性预测试”方法。样本中略多于61%的人报告睡眠质量恶化，这与认知性抑郁显著相关（ = .346， = .007）。在特定症状水平上， 对 的方差有显著贡献（R变化 = .140，变化的 = 9.298， = .003）。睡眠困难，尤其是入睡困难，在前列腺癌患者中很常见，并且与因清晰思考能力下降而导致的抑郁有关。这可能会对前列腺癌男性理解其治疗方案并做出相关决策的能力产生不利影响。
