Brain-Behaviour Research Group, School of Science & Technology, University of New England, Armidale, NSW 2351, Australia.
Genesiscare, John Flynn Private Hospital, Tugun, QLD 4224, Australia.
Int J Environ Res Public Health. 2022 Jul 12;19(14):8505. doi: 10.3390/ijerph19148505.
This study aimed to investigate the moderating effect of psychological resilience on sleep-deterioration-related depression among patients with prostate cancer, in terms of the total score and individual symptoms. From a survey of 96 patients with prostate cancer, 55 who reported a deterioration in their sleep quality since diagnosis and treatment completed the Zung Self-Rating Depression Scale, Connor-Davidson Resilience Scale, and the Insomnia Severity Index. Moderation analysis was conducted for the scale total scores and for the 'core' symptoms of each scale within this sample, based on data analysis. Interaction analysis was used to identify key associations. The moderation analysis suggested that psychological resilience moderated the depressive effect of sleep deterioration that patients reported occurred after their diagnosis and treatment and did so at the total and 'core' symptom levels of being able to see the humorous side of things and to think clearly when under pressure, but there was an interaction between this moderating effect, the strength of psychological resilience, and severity of sleep deterioration. Although it appears to be a successful moderator of depression arising from sleep deterioration that was reported by patients with prostate cancer, the effectiveness of psychological resilience is conditional upon the severity of patients' sleep difficulties and the strength of their psychological resilience. Implications for the application of resilience training and concomitant therapies for patients with prostate cancer with sleep difficulties and depression are discussed.
本研究旨在探讨心理弹性对前列腺癌患者睡眠恶化相关抑郁的调节作用，包括总分和个体症状。在对 96 名前列腺癌患者的调查中，55 名报告自诊断和治疗以来睡眠质量恶化的患者完成了zung 自评抑郁量表、Connor-Davidson 韧性量表和失眠严重程度指数。基于数据分析，对量表总分和样本中每个量表的“核心”症状进行了调节分析。采用交互分析来识别关键关联。调节分析表明，心理弹性调节了患者报告的诊断和治疗后睡眠恶化的抑郁效应，并且在能够看到事物幽默面和在压力下清晰思考的能力等“核心”症状的总分和症状水平上具有调节作用，但这种调节效应、心理弹性的强度和睡眠恶化的严重程度之间存在相互作用。虽然心理弹性似乎是成功地调节了前列腺癌患者报告的睡眠恶化引起的抑郁，但心理弹性的有效性取决于患者睡眠困难的严重程度和心理弹性的强度。讨论了针对有睡眠困难和抑郁的前列腺癌患者应用韧性训练和伴随治疗的意义。
