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一项随机临床试验中自我催眠放松应用对疼痛和焦虑的疗效：积极和对照应用设计的结果和考虑。

Efficacy of a Self-Hypnotic Relaxation App on Pain and Anxiety in a Randomized Clinical Trial: Results and Considerations on the Design of Active and Control Apps.

机构信息

Hypnalgesics, LLC, Brookline, Massachusetts, USA.

Craniofacial Pain Center, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.

出版信息

Int J Clin Exp Hypn. 2021 Apr-Jun;69(2):277-295. doi: 10.1080/00207144.2021.1883988. Epub 2021 Mar 16.

DOI:10.1080/00207144.2021.1883988
PMID:33724898
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9976960/
Abstract

Despite an explosion of mobile app offerings for management of pain and anxiety, the evidence for effectiveness is scarce. Placebo-controlled trials are the most desirable but designing inactive placebo apps can be challenging. For a prospective randomized clinical trial with 72 patients in a craniofacial pain center, we created an app with self-hypnotic relaxation (SHR) for use with iOS and Android systems. A placebo background audio (BA) app was built with the same look and functionality. Both iOS and Android SHR apps alone and in comparison to the BA group significantly reduced pain and anxiety during the waiting-room time. The Android BA app significantly reduced anxiety but not pain. The iOS BA app affected neither pain nor anxiety, functioning as an ideal placebo. Usage analysis revealed that different default approaches of the iOS and Android devices accounted for the difference in results.

摘要

尽管有大量的移动应用程序可用于疼痛和焦虑管理，但有效的证据却很少。安慰剂对照试验是最理想的，但设计无效的安慰剂应用程序可能具有挑战性。为了在颅面疼痛中心进行一项有 72 名患者的前瞻性随机临床试验，我们创建了一个具有自我催眠放松 (SHR) 功能的应用程序，适用于 iOS 和 Android 系统。我们还构建了一个具有相同外观和功能的安慰剂背景音频 (BA) 应用程序。仅使用 iOS 和 Android SHR 应用程序，以及与 BA 组进行比较，都能显著减轻候诊室期间的疼痛和焦虑。Android BA 应用程序显著减轻了焦虑，但对疼痛没有影响。iOS BA 应用程序对疼痛和焦虑均无影响，是理想的安慰剂。使用情况分析表明，iOS 和 Android 设备的不同默认方法导致了结果的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2658/9976960/6fd0d9ef8a5e/nihms-1870647-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2658/9976960/7d719ada234e/nihms-1870647-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2658/9976960/9551c8953770/nihms-1870647-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2658/9976960/58b7a7afb546/nihms-1870647-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2658/9976960/6fd0d9ef8a5e/nihms-1870647-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2658/9976960/7d719ada234e/nihms-1870647-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2658/9976960/9551c8953770/nihms-1870647-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2658/9976960/58b7a7afb546/nihms-1870647-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2658/9976960/6fd0d9ef8a5e/nihms-1870647-f0004.jpg

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