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2 型糖尿病伴精神分裂症患者:一项基于人群的 8 年观察性研究。

Schizophrenic patients with type 2 diabetes: An 8-year population-based observational study.

机构信息

Department of Education and Research in Health Sciences, Faculty of Health Sciences, Medical University of Warsaw, Warsaw, Poland.

Department of Analysis and Strategy, The National Health Fund, Warsaw, Poland.

出版信息

PLoS One. 2021 Mar 16;16(3):e0248407. doi: 10.1371/journal.pone.0248407. eCollection 2021.

DOI:10.1371/journal.pone.0248407
PMID:33724988
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7963070/
Abstract

This paper presents a realistic evaluation of the prevalence of type 2 diabetes mellitus (T2DM) among Polish schizophrenic patients who have sought treatment through the Polish National Health Fund in the years 2010-2017. Data from the National Health Fund database was used and T2DM and schizophrenia groups were defined according to International Classification of Diseases (ICD-10) codes. Demographic data were collected from the web page of Statistics Poland (GUS). The annual prevalence of T2DM and schizophrenia was estimated, and the age groups were categorised into eight sets. The incidence of schizophrenia in T2DM patients in the years 2010-2017 was measured, including relative risk and 95% confidence interval (95% CI). The incidence of T2DM has been assessed in various subtypes of schizophrenia. In the eight years of follow-up study, 1,481,642 patients with schizophrenia were included, of which 185,205 were also diagnosed with T2DM. This accounted for 12.50% of all patients with schizophrenia. The trend of comorbid schizophrenia (F20) and T2DM (E11) in the general population of patients with schizophrenia, who sought treatment through the National Health Fund, was relatively stable in the years 2010-2017. The relative risk of T2DM in those with schizophrenia was 8.33 (95% CI 8.23-8.43) in 2017. Taking actions to enable the detection of diabetes in patients with concomitant schizophrenia is well-grounded, although these actions should be gender-dependent. There is also a need to take adequate actions to improve the efficiency of diabetological care among patients with schizophrenia.

摘要

本文对 2010 年至 2017 年期间通过波兰国家卫生基金(National Health Fund)寻求治疗的波兰精神分裂症患者中 2 型糖尿病(T2DM)的患病率进行了现实评估。研究使用了国家卫生基金数据库的数据,并根据国际疾病分类(ICD-10)代码定义了 T2DM 和精神分裂症组。人口统计学数据来自波兰统计局(GUS)的网页。估计了 T2DM 和精神分裂症的年度患病率,并将年龄组分为八组。测量了 2010 年至 2017 年期间 T2DM 患者中精神分裂症的发病率,包括相对风险和 95%置信区间(95%CI)。还评估了各种亚型精神分裂症中 T2DM 的发病率。在八年的随访研究中,纳入了 1481642 例精神分裂症患者,其中 185205 例患者还被诊断为 T2DM。这占所有精神分裂症患者的 12.50%。在通过国家卫生基金寻求治疗的精神分裂症患者总体人群中,共病精神分裂症(F20)和 T2DM(E11)的趋势在 2010 年至 2017 年期间相对稳定。2017 年,精神分裂症患者 T2DM 的相对风险为 8.33(95%CI 8.23-8.43)。采取行动在伴发精神分裂症的患者中检测糖尿病是有充分依据的,尽管这些行动应根据性别而定。还需要采取充分的行动,提高精神分裂症患者的糖尿病护理效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94cb/7963070/c94b9c29be07/pone.0248407.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94cb/7963070/daa801d5ee25/pone.0248407.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94cb/7963070/c94b9c29be07/pone.0248407.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94cb/7963070/daa801d5ee25/pone.0248407.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94cb/7963070/c94b9c29be07/pone.0248407.g002.jpg

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