Holler Mareike, Koranyi Susan, Strauss Bernhard, Rosendahl Jenny
Friedrich Schiller University, Jena, Germany.
Leipzig University, Germany.
Clin Psychol Rev. 2021 Apr;85:102001. doi: 10.1016/j.cpr.2021.102001. Epub 2021 Mar 1.
In this meta-analysis we updated a review from 2013 investigating the evidence on the efficacy of hypnosis in adults undergoing surgical procedures compared to standard care alone or an attention control. A comprehensive literature search using Medline, CENTRAL, Web of Science, PsycINFO, ProQuest Dissertations and Theses database, and manual searches were conducted to identify randomized controlled trials. In this update, N = 23 eligible studies were added to the existing study pool, resulting in N = 50 studies with 4269 patients. Random effects meta-analyses revealed positive treatment effects on mental distress (g = 0.55, 95% CI [0.39; 0.70], NNT = 3.32), pain (g = 0.37, 95% CI [0.25; 0.50], NNT = 4.78), medication consumption (g = 0.46, 95% CI [0.23; 0.68], NNT = 3.95), recovery (g = 0.26, 95% CI [0.09; 0.42], NNT = 6.91), and surgical procedure time (g = 0.23, 95% CI [0.14; 0.33], NNT = 7.6). No effects were found for physiological parameters (g = 0.13, 95% CI [-0.06; 0.33], NNT = 13.26). 95% prediction intervals included the null effect for all outcomes except for procedure time. In conclusion, although positive effects of hypnosis could be shown, overall generalizability is limited due to high heterogeneity of the study results that could not be explained by characteristics of patients, interventions, or study methods.
在这项荟萃分析中，我们更新了2013年的一篇综述，该综述调查了与单独的标准护理或注意力控制相比，催眠对接受外科手术的成年人的疗效证据。使用Medline、CENTRAL、科学网、PsycINFO、ProQuest学位论文数据库进行了全面的文献检索，并进行了手动检索以识别随机对照试验。在本次更新中，将N = 23项符合条件的研究添加到现有的研究库中，从而有N = 50项研究，涉及4269名患者。随机效应荟萃分析显示，催眠对精神痛苦（g = 0.55，95%CI [0.39; 0.70]，NNT = 3.32）、疼痛（g = 0.37，95%CI [0.25; 0.50]，NNT = 4.78）、药物消耗（g = 0.46，95%CI [0.23; 0.68]，NNT = 3.95）、恢复（g = 0.26，95%CI [0.09; 0.42]，NNT = 6.91）和外科手术时间（g = 0.23，95%CI [0.14; 0.33]，NNT = 7.6）有积极的治疗效果。未发现对生理参数有影响（g = 0.13，95%CI [-0.06; 0.33]，NNT = 13.26）。除手术时间外，所有结局的95%预测区间都包括无效效应。总之，虽然可以显示催眠的积极效果，但由于研究结果的高度异质性无法通过患者特征、干预措施或研究方法来解释，总体可推广性有限。
