Department of Neurology, Hanyang Hospital of Wuhan.
Department of Neurology, the Fourth Hospital of Wuhan.
Medicine (Baltimore). 2021 Mar 12;100(10):e23825. doi: 10.1097/MD.0000000000023825.
Vertigo is a well-known presenting complaint common in the main care offices as well as departments. It is also regarded as a symptom of vestibular dysfunction and has been expressed as a feeling of motion, specifically rotational motion. As patients grow older, vertigo also becomes a commonly presenting complaint. The current study will carry out a widespread systematic review to estimate clinical therapeutic effects of gastrodin in combination with betahistine on vertigo.
We will systematically search different databases, including PubMed, EMBASE, Web of Science, the Cochrane Library, Chinese BioMedical Literature Database (CBM), China National Knowledge Infrastructure Database (CNKI), and WanFang to collect the randomised controlled studies that evaluate the efficiency of gastrodin and betahistine in treating patients with vertigo from their inception to November 2020. However, only studies in English or Chinese will be included. Two authors will independently perform selection, data extraction, and assessment of risk of bias for the included papers. Accordingly, any disagreements between the independent authors will be addressed via discussion or by consulting a third author when needful. Additionally, we will use RevMan 5.3 software to perform the data synthesis.
The efficiency of gastrodin and betahistine in treating patients with vertigo will be systematically evaluated.
The current study aims to stipulate more consistent substantiation to explore whether gastrodin combined with betahistine is more effective for the treatment of vertigo.
DOI 10.17605/OSF.IO/HQTZA (https://osf.io/hqtza/).
眩晕是一种常见的主诉，在基层医疗机构和各科室都很常见。它也被认为是前庭功能障碍的一种症状，表现为运动感，特别是旋转运动感。随着患者年龄的增长，眩晕也成为常见的主诉。本研究将进行广泛的系统评价，以评估天麻素联合倍他司汀治疗眩晕的临床疗效。
我们将系统地检索包括 PubMed、EMBASE、Web of Science、Cochrane 图书馆、中国生物医学文献数据库（CBM）、中国知网（CNKI）和万方在内的不同数据库，以收集从成立到 2020 年 11 月评估天麻素和倍他司汀治疗眩晕患者疗效的随机对照研究。但仅纳入英文或中文的研究。两位作者将独立地进行选择、数据提取和纳入研究的偏倚风险评估。如有分歧，将通过讨论或必要时咨询第三位作者解决。此外，我们将使用 RevMan 5.3 软件进行数据合成。
将系统评价天麻素和倍他司汀治疗眩晕患者的疗效。
本研究旨在为探讨天麻素联合倍他司汀治疗眩晕是否更有效提供更一致的证据。
DOI 10.17605/OSF.IO/HQTZA（https://osf.io/hqtza/）。
