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妊娠合并垂体瘤卒中伴脑桥外髓鞘溶解症 1 例报告

Pituitary tumor apoplexy associated with extrapontine myelinolysis during pregnancy: A case report.

机构信息

Department of Obstetrics and Gynecology.

Department of Radiology.

出版信息

Medicine (Baltimore). 2021 Mar 12;100(10):e25075. doi: 10.1097/MD.0000000000025075.

Abstract

RATIONALE

Pituitary tumor apoplexy (PTA) is a rare clinical syndrome which requires urgent diagnosis and treatment due to its life-threatening consequences. Management of undiagnosed pituitary tumor before pregnancy is a problem during pregnancy.

PATIENT CONCERNS

We reported a case with PTA which was not diagnosed before pregnancy presenting with vomiting associated with hyponatremia during the third trimester. After supplying the sodium the patient presented with dysarthria and hemiplegia.

DIAGNOSES

MRI examination showed PTA accompanied with extrapontine myelinolysis (EPM).

INTERVENTIONS

The patient was given hydrocortisone according to the symptoms gradually to taper off dose, at the same times oral levothyroxine therapy (25μg/day) was given.

OUTCOMES

The patient delivered a healthy baby via cesarean section at hospital at 38 + 1 week of gestation. We performed MRI examination regularly and the tumor regressed significantly 8 months postpartum.

LESSONS

We reported a case as PTA associated with EPM. Headache during pregnancy is often nonspecific, so careful medical history inquiry is very important.

摘要

背景

垂体瘤卒中(PTA)是一种罕见的临床综合征,由于其危及生命的后果,需要紧急诊断和治疗。妊娠前未诊断的垂体瘤的管理是妊娠期间的一个问题。

病例介绍

我们报告了一例妊娠晚期因呕吐伴低钠血症而出现未诊断的 PTA 病例。补钠后,患者出现构音障碍和偏瘫。

诊断

MRI 检查显示 PTA 伴有桥外髓鞘溶解症(EPM)。

干预措施

根据症状逐渐给予患者氢化可的松逐渐减量,同时给予口服左甲状腺素治疗(25μg/天)。

结果

患者于 38+1 周妊娠时在医院行剖宫产分娩一健康婴儿。我们定期进行 MRI 检查,产后 8 个月肿瘤明显消退。

结论

我们报告了一例与 EPM 相关的 PTA 病例。妊娠期间头痛通常是非特异性的,因此仔细询问病史非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88c1/7969261/628a65e6100b/medi-100-e25075-g001.jpg

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