Opt Express. 2021 Mar 1;29(5):6563-6581. doi: 10.1364/OE.412640.
Focusing light into highly disordered biological tissue is a major challenge in optical microscopy and biomedical imaging due to scattering. However, correlations in the scattering matrix, known as "memory effects", can be used to improve imaging capabilities. Here we discuss theoretically and numerically the possibility to achieve three-dimensional ultrashort laser focusing and scanning inside forward scattering media, beyond the scattering mean free path, by simultaneously taking advantage of the angular and the chromato-axial memory effects. The numerical model is presented in details, is validated within the state of the art theoretical and experimental framework and is finally used to propose a scheme for focusing ultra-short laser pulses in depth through forward scattering media.
聚焦光进入高度无序的生物组织是光学显微镜和生物医学成像中的一个主要挑战,这是由于散射造成的。然而,散射矩阵中的相关性,即所谓的“记忆效应”,可以被用来提高成像能力。在这里,我们从理论和数值两个方面讨论了通过同时利用角度和色轴记忆效应,在超越散射平均自由程的情况下,实现三维超短激光聚焦和扫描的可能性。我们详细介绍了数值模型,在当前的理论和实验框架内对其进行了验证,最后提出了一种通过前向散射介质对超短激光脉冲进行深度聚焦的方案。