Wang Guojun, Jia Cunxian, Ma Zhenyu, Zhou Liang
Shenzhen Graduate School, Peking University, Shenzhen, China.
Department of Public Health, Shenzhen Kangning Hospital, Shenzhen, China.
Aust N Z J Psychiatry. 2022 May;56(5):560-568. doi: 10.1177/0004867421998804. Epub 2021 Mar 16.
Physical diseases are well-established risk factor for suicide, particularly among older adults. However, little is known about the underlying mechanism of the association. This study aimed to describe the prevalence of physical diseases and their influences on the elderly in rural China and to examine the underlying mechanisms of the relationship between physical diseases and suicide.
This matched case-control psychological autopsy study was conducted from June 2014 to September 2015. Consecutive suicide cases (242) among people aged 60 years or above were identified in three Chinese provinces. The suicide cases were 1:1 matched with living comparisons based on age, gender and residential area. Two informants for each participant were interviewed to collect data on their demographic characteristics, the severity index of physical diseases, depressive symptoms, feelings of hopelessness, mental disorders and social support.
A significant difference was found between suicide cases and living comparisons regarding the prevalence of physical diseases (83.5% vs 66.5%, < 0.001) and their severity (11.3 ± 6.2 vs 6.7 ± 5.3, < 0.001). Independent risks of suicide included the following: not currently married (OR = 2.81, 95% CI = [1.04, 7.62]), mental disorders (OR = 7.18, 95% CI = [1.83, 28.13]), depressive symptoms (OR = 1.15, 95% CI = [1.05, 1.26]) and feelings of hopelessness (OR = 1.51, 95% CI = [1.20, 1.90]). The structural equation model indicated that the relationship between the severity index of physical diseases and suicide was mediated by depressive symptoms, feelings of hopelessness and mental disorders.
The severity and number of physical diseases were found to be correlated with suicide among the elderly in rural China, after controlling for demographic characteristics. Physical diseases elevate one's suicide risk by increasing depressive symptoms, feelings of hopelessness and mental disorders. Efforts for suicide prevention should be integrated with strategies to treat physical diseases along with psychological interventions.
身体疾病是公认的自杀风险因素,在老年人中尤为如此。然而,对于这种关联的潜在机制知之甚少。本研究旨在描述中国农村地区身体疾病的患病率及其对老年人的影响,并探讨身体疾病与自杀之间关系的潜在机制。
本匹配病例对照心理解剖学研究于2014年6月至2015年9月进行。在中国三个省份确定了60岁及以上人群中的连续自杀病例(242例)。自杀病例与基于年龄、性别和居住地区的在世对照进行1:1匹配。对每位参与者的两名 informant 进行访谈,以收集他们的人口统计学特征、身体疾病严重程度指数、抑郁症状、绝望感、精神障碍和社会支持方面的数据。
在身体疾病患病率(83.5% 对66.5%,<0.001)及其严重程度(11.3±6.2对6.7±5.3,<0.001)方面,自杀病例与在世对照之间存在显著差异。自杀的独立风险因素包括:目前未婚(OR = 2.81,95%CI = [1.04, 7.62])、精神障碍(OR = 7.18,95%CI = [1.83, 28.13])、抑郁症状(OR = 1.15,95%CI = [1.05, 1.26])和绝望感(OR = 1.51,95%CI = [1.20, 1.90])。结构方程模型表明,身体疾病严重程度指数与自杀之间的关系是由抑郁症状、绝望感和精神障碍介导的。
在控制人口统计学特征后,发现中国农村老年人身体疾病的严重程度和数量与自杀相关。身体疾病通过增加抑郁症状、绝望感和精神障碍来提高一个人的自杀风险。自杀预防工作应与治疗身体疾病的策略以及心理干预相结合。