Beck H I, Brandrup F, Hagdrup H K, Jensen N K, Starklint H
Department of Dermatology, Odense University Hospital, Denmark.
J Cutan Pathol. 1988 Apr;15(2):124-8. doi: 10.1111/j.1600-0560.1988.tb00532.x.
A case of reactive perforating collagenosis in an adult male patient with chronic renal failure. Pruritic, umbilicate papules, showing extrusion of collagen fibers through the epidermis were detected histopathologically. Electron microscopy showed absence of basal membrane beneath the perforation and collagen fibers with preserved periodicity passing through widened intercellular spaces with islands of cytoplasmic material.
一名患有慢性肾功能衰竭的成年男性患者发生反应性穿通性胶原病的病例。组织病理学检查发现有瘙痒性脐凹状丘疹,显示胶原纤维穿过表皮。电子显微镜检查显示穿孔下方无基底膜,胶原纤维周期性保存,穿过增宽的细胞间隙并伴有细胞质物质岛。