Cooper Laura E, O'Toole Megan C, Fields Kristopher L, Eriksson Elof K, Chan Rodney K
Department of Surgery, University of Maryland Medical Center, Baltimore, Md.
STARS Plastic Surgery, San Antonio, Tex.
Plast Reconstr Surg Glob Open. 2021 Mar 11;9(3):e3455. doi: 10.1097/GOX.0000000000003455. eCollection 2021 Mar.
Closed incision negative pressure therapy (ciNPT) has been shown to improve wound healing for patients at high risk for wound complications. Current devices consist of opaque interface dressings that do not allow ongoing visual evaluation of the surgical incision and utilize a negative pressure of -80 mm Hg to -125 mm Hg. The Negative Pressure Platform Wound Dressing (NP-PWD) was developed to address these aspects. This case series is the first evaluation of the NP-PWD in a clinical setting.
Patients aged 18-85 undergoing an operation with an anticipated incision and primary closure were screened. Demographics, comorbidities, and operation performed were recorded. Following closure, the incision was measured and photographed before NP-PWD placement. The NP-PWD was removed at the first postoperative check (POC) between postoperative days (PODs) 3-5. Subjects were followed until PODs 9-14. POCs consisted of incision assessment, measurement, photography, and adverse event monitoring.
A total of 8 patients with 10 incisions were included in the study. Five patients were men. Median age was 56 years (IQR 53-74 years). All incisions were intact and without inflammation or infection at all POCs. Three adverse events, including small blisters and interruption of therapy, were noted.
This case series reports that patients tolerated the NP-PWD on closed surgical incisions well and that all incisions were intact without evidence of inflammation or infection after 2 weeks of follow-up. Future controlled, clinical studies should further examine the safety and efficacy of the use of the NP-PWD.
闭合切口负压疗法(ciNPT)已被证明可改善有伤口并发症高风险患者的伤口愈合情况。目前的设备包括不透明的界面敷料,无法对手术切口进行持续的视觉评估,且使用-80毫米汞柱至-125毫米汞柱的负压。负压平台伤口敷料(NP-PWD)就是为解决这些问题而研发的。本病例系列是对NP-PWD在临床环境中的首次评估。
筛选年龄在18至85岁之间、预期进行手术切口并一期缝合的患者。记录人口统计学资料、合并症和所进行的手术。缝合后,在放置NP-PWD之前对切口进行测量和拍照。在术后第3至5天之间的首次术后检查(POC)时移除NP-PWD。对受试者进行随访直至术后第9至14天。POC包括切口评估、测量、拍照和不良事件监测。
本研究共纳入8例患者的10个切口。5例为男性。中位年龄为56岁(四分位间距53 - 74岁)。在所有POC时,所有切口均完整,无炎症或感染。记录到3例不良事件,包括小水泡和治疗中断。
本病例系列报告称,患者对闭合手术切口使用NP-PWD耐受性良好,且在随访2周后所有切口均完整,无炎症或感染迹象。未来的对照临床研究应进一步检验使用NP-PWD的安全性和有效性。