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强直性脊柱炎患者的吞咽困难:一例报告。

Dysphagia in a patient with ankylosing spondylitis: A case report.

作者信息

Wang Xin-Wen, Zhang Wen-Zhi

机构信息

Department of Orthopedics, Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, Anhui Province, China.

Spine Center, Department of Orthopedics, Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, Anhui Province, China.

出版信息

World J Clin Cases. 2021 Mar 6;9(7):1639-1645. doi: 10.12998/wjcc.v9.i7.1639.

DOI:10.12998/wjcc.v9.i7.1639
PMID:33728307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7942043/
Abstract

BACKGROUND

Ankylosing spondylitis (AS) is a systematic and rheumatic disease, which causes multiple symptoms. However, dysphagia due to the formation of a giant anterior cervical osteophyte is rare in patients with AS.

CASE SUMMARY

We present the case of a 65-year-old male patient who was diagnosed with AS and visited the hospital with a complaint of progressive dysphagia. The appropriate imaging examinations indicated that a giant anterior cervical osteo-phyte at C3-4 caused esophageal compression, which led to dysphagia. An operation for resection was performed without complications.

CONCLUSION

This case demonstrates that a large cervical osteophyte may be the cause of dysphagia in patients with AS, and early accurate diagnosis and surgical treat-ment are very important for the improvement of symptoms. Anterior cervical discectomy and fusion are extremely effective and should be taken into consideration.

摘要

背景

强直性脊柱炎(AS)是一种系统性风湿性疾病,可引发多种症状。然而,AS患者因形成巨大的颈椎前路骨赘而导致吞咽困难的情况较为罕见。

病例摘要

我们报告一例65岁男性患者,该患者被诊断为AS,因进行性吞咽困难前来就诊。适当的影像学检查表明,C3-4水平的巨大颈椎前路骨赘压迫食管,导致吞咽困难。患者接受了切除手术,未出现并发症。

结论

该病例表明,巨大的颈椎骨赘可能是AS患者吞咽困难的原因,早期准确诊断和手术治疗对于改善症状非常重要。颈椎前路椎间盘切除融合术极为有效,应予以考虑。

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本文引用的文献

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HLA-B27 Negativity Is Associated With Renal Function Decline in Patients With Ankylosing Spondylitis and Secondary IgA Nephropathy.HLA - B27阴性与强直性脊柱炎继发IgA肾病患者的肾功能下降有关。
Front Med (Lausanne). 2020 Apr 7;7:89. doi: 10.3389/fmed.2020.00089. eCollection 2020.
2
Long-term results after surgical treatment of diffuse idiopathic skeletal hyperostosis (DISH) causing dysphagia.手术治疗弥漫特发性骨肥厚(DISH)导致吞咽困难的长期结果。
J Clin Neurosci. 2019 Sep;67:151-155. doi: 10.1016/j.jocn.2019.05.057. Epub 2019 Jun 17.
3
Dysphagia due to DISH-related anterior osteophytes: DISHphagia!!
强直性脊柱炎患者胸段脊髓损伤后迅速进展的吞咽困难:一例报告
Geriatr Orthop Surg Rehabil. 2023 Mar 2;14:21514593231159353. doi: 10.1177/21514593231159353. eCollection 2023.
弥漫性特发性骨肥厚(DISH)相关的前路骨赘导致的吞咽困难:“DISH吞咽困难”!!
BMJ Case Rep. 2017 Oct 15;2017:bcr-2017-222512. doi: 10.1136/bcr-2017-222512.
4
Pathogenesis of ankylosing spondylitis - recent advances and future directions.强直性脊柱炎的发病机制——最新进展与未来方向。
Nat Rev Rheumatol. 2017 Jun;13(6):359-367. doi: 10.1038/nrrheum.2017.56. Epub 2017 Apr 27.
5
Dysphagia Related to Esophagus Compression by Anterior Cervical Ossification in a Patient with Ankylosing Spondylitis.强直性脊柱炎患者因颈椎前路骨化导致食管受压引起的吞咽困难
J Rheumatol. 2015 Oct;42(10):1922-3. doi: 10.3899/jrheum.150449.
6
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