Meyer Barbara, Graf Lukas, Endermann Susann
Klinik für Anästhesiologie, Intensiv‑, Rettungs- und Schmerzmedizin, Kantonsspital St. Gallen, Rorschacherstraße 95, 9000, St. Gallen, Schweiz.
Zentrum für Labormedizin, Kantonsspital St. Gallen, Frohbergstraße 3, 9000, St. Gallen, Schweiz.
Anaesthesist. 2021 Jul;70(7):598-602. doi: 10.1007/s00101-021-00939-2. Epub 2021 Mar 16.
Immune thrombozytopenia (ITP) is a rare acquired thrombocytopenia occurring in 2 to 4 persons per 100,000 per year. ITP is defined as a platelet count less than 100 G/l in patients in whom other causes of thrombocytopenia have been ruled out. Severe bleeding is rare but may constitute a life-threatening condition. Therapeutic options include platelet transfusions, glucocorticoids and intravenous immune globuline (IVIG). Emergency splenectomy has to be considered in otherwise untreatable bleeding. We present the case of a 65-year-old patient with chronic refractory ITP and finally fatal bleeding.
免疫性血小板减少症（ITP）是一种罕见的获得性血小板减少症，每年每10万人中有2至4人发病。ITP的定义为在排除其他血小板减少原因的患者中，血小板计数低于100 G/l。严重出血很少见，但可能构成危及生命的状况。治疗选择包括血小板输注、糖皮质激素和静脉注射免疫球蛋白（IVIG）。对于无法治疗的出血情况，必须考虑紧急脾切除术。我们报告一例65岁慢性难治性ITP患者最终因出血死亡的病例。
