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年轻人皮肤光老化:皮肤成像技术的临床研究。

Skin photoaging in young men: A clinical study by skin imaging techniques.

机构信息

School of Pharmaceutical Sciencies of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

Medical School - Federal University of São Paulo, Ribeirão Preto, Brazil.

出版信息

Int J Cosmet Sci. 2021 Jun;43(3):341-351. doi: 10.1111/ics.12701. Epub 2021 Apr 21.

Abstract

OBJECTIVE

Differences in skin physiology and lifestyle among people can influence the skin damage caused by solar radiation. Photoprotection habits play an important role to prevent skin photoaging. Thus, the objective of the present study was to evaluate the skin changes resulting from solar exposure in young men by skin imaging techniques.

METHODS

Twenty-three male, aged 18-28 years, with and without photoprotection habits participated in the study. Instrumental measurements in terms of dermis thickness and echogenicity (20 mHz ultrasound - DermaScanC ), morphological and structural skin characterization (Reflectance Confocal Microscopy - VivaScope 1500) and high-resolution imaging (Visioface ) were performed in the malar region of the face.

RESULTS

Pigmentation disorders, telangiectasia, wrinkles and lower dermis echogenicity were observed in the skin of subjects without photoprotection habits. Reflectance Confocal Microscopy images showed an irregular honeycomb pattern (35%), polycyclic papillae (40%) and coarse collagen fibres (35%), which are related to photoaging.

CONCLUSION

Sun exposure without photoprotection results in a loss of dermal echogenicity and changes in the epidermis structure and collagen fibres regardless of chronological age. Thus, the study adds data for a discussion about correct photoprotection habits among young people and can help to increase the use of sunscreens for male public.

摘要

目的

人体皮肤的生理学和生活方式的差异会影响因太阳辐射导致的皮肤损伤。光保护习惯在预防皮肤光老化方面起着重要作用。因此,本研究的目的是通过皮肤成像技术评估年轻男性因太阳照射导致的皮肤变化。

方法

本研究纳入了 23 名年龄在 18-28 岁之间、有或没有光保护习惯的男性。在面部颧骨区域,对面部皮肤进行了真皮厚度和超声回声(20MHz 超声 - DermaScanC)、形态和结构皮肤特征(反射共聚焦显微镜 - VivaScope 1500)以及高分辨率成像(Visioface)的仪器测量。

结果

未采取光保护措施的受试者皮肤出现色素紊乱、毛细血管扩张、皱纹和真皮回声降低。反射共聚焦显微镜图像显示不规则的蜂窝状模式(35%)、多环乳头(40%)和粗胶原纤维(35%),这些都是与光老化相关的特征。

结论

无论实际年龄如何,没有光保护的太阳照射会导致真皮回声降低,以及表皮结构和胶原纤维的变化。因此,该研究为讨论年轻人的正确光保护习惯提供了数据,并有助于增加男性对防晒霜的使用。

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