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巴西塞阿拉州 1970 年至 2019 年人类狂犬病流行病学。

Epidemiology of human rabies in the state of Ceará, Brazil, 1970 to 2019.

机构信息

Universidade Federal do Ceará, Programa de Pós-Graduação em Saúde Pública, Fortaleza, CE, Brasil.

Universidade de Fortaleza, Centro de Ciências da Saúde, Fortaleza, CE, Brasil.

出版信息

Epidemiol Serv Saude. 2021 Mar 12;30(1):e2020354. doi: 10.1590/S1679-49742021000100010. eCollection 2021.

Abstract

OBJECTIVE

To describe cases of human rabies in Ceará State, Brazil between 1970 and 2019.

METHODS

This was a descriptive study using secondary data from the Ceará State Department of Health and the state reference hospital.

RESULTS

Of 171 cases, 75.7% occurred in males, 60.0% in <19-year-olds, and 56.0% in urban areas. Rabies was transmitted by dogs in 74.0% of cases, marmosets in 16.7% and bats in 7.3%. Between 1970 and 1978, there was an increase of cases (using the Joinpoint Regression Program, annual percentage change [APC] = 13.7 - 95%CI 4.6;41.5), while between 1978 and 2019 there was a decrease (APC = -6.7 - 95%CI -8.8;-5.9). There was a reduction in transmission by dogs (71 cases, last case in 2010) and an increase by sylvatic animals (5 cases since 2005).

CONCLUSION

This study demonstrates changes in rabies transmission dynamics during the period studied, with a reduction in transmission by dogs and an increase of transmission by sylvatic animals.

摘要

目的

描述 1970 年至 2019 年巴西塞阿拉州的人类狂犬病病例。

方法

这是一项使用塞阿拉州卫生部和州立参考医院的二级数据的描述性研究。

结果

在 171 例病例中,75.7%为男性,60.0%为<19 岁,56.0%为城市地区。狂犬病传播途径中,74.0%由狗传播,16.7%由狨猴传播,7.3%由蝙蝠传播。1970 年至 1978 年期间病例数量增加(使用 Joinpoint 回归程序,年变化百分比[APC]为 13.7-95%CI 4.6;41.5),而 1978 年至 2019 年期间则减少(APC=-6.7-95%CI-8.8;-5.9)。狗传播的病例数量减少(71 例,最后一例发生在 2010 年),而野生动物传播的病例数量增加(自 2005 年以来有 5 例)。

结论

本研究表明,在研究期间,狂犬病传播动力学发生了变化,狗传播的病例数量减少,野生动物传播的病例数量增加。

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