Ramos Mauro Cunha, Sardinha José Carlos, Alencar Herculano Duarte Ramos de, Aragón Mayra Gonçalves, Lannoy Leonor Henriette de
Secretaria de Estado de Saúde do Rio Grande do Sul, Ambulatório de Dermatologia Sanitária, Porto Alegre, RS, Brasil.
Fundação de Dermatologia Tropical e Venerologia Alfredo da Matta, Manaus, AM, Brasil.
Epidemiol Serv Saude. 2021 Mar 15;30(spe1):e2020663. doi: 10.1590/S1679-4974202100010.esp1. eCollection 2021.
Infections that cause genital ulcers are one of the themes comprising the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health in 2020. The Protocol and Guidelines have been developed based on scientific evidence and validated in discussions with specialists. This article addresses clinical genital ulcer syndrome caused by sexually transmitted infections, and its most common etiological agents: Treponema pallidum (syphilis), herpes simplex virus-2 (genital herpes) and herpes simplex virus-1 (perioral herpes), Haemophilus ducreyi (chancroid), Chlamydia trachomatis serotypes L1, L2 and L3 (venereal lymphogranuloma), and Klebsiella granulomatis (donovanosis). Epidemiological and clinical aspects of these infections are presented, as well as guidelines for their diagnosis and treatment, in addition to strategies for surveillance, prevention and control actions, with the purpose of supporting health managers and professionals in the qualification of care.
导致生殖器溃疡的感染是巴西卫生部于2020年发布的《性传播感染患者综合护理临床方案和治疗指南》所涵盖的主题之一。该方案和指南是基于科学证据制定的，并在与专家的讨论中得到验证。本文论述了由性传播感染引起的临床生殖器溃疡综合征及其最常见的病原体：梅毒螺旋体（梅毒）、单纯疱疹病毒2型（生殖器疱疹）和单纯疱疹病毒1型（唇疱疹）、杜克雷嗜血杆菌（软下疳）、沙眼衣原体L1、L2和L3血清型（性病性淋巴肉芽肿）以及肉芽肿克雷伯菌（腹股沟肉芽肿）。文中介绍了这些感染的流行病学和临床方面，以及诊断和治疗指南，此外还介绍了监测、预防和控制措施的策略，旨在支持卫生管理人员和专业人员提高护理质量。
