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Phase III Clinical Trials in First-Line Follicular Lymphoma: A Review of Their Design and Interpretation.一线滤泡性淋巴瘤的 III 期临床试验：设计与解读综述。
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本文引用的文献

1
Association of early disease progression and very poor survival in the GALLIUM study in follicular lymphoma: benefit of obinutuzumab in reducing the rate of early progression.滤泡性淋巴瘤GALLIUM研究中早期疾病进展与极低生存率的关联：奥妥珠单抗在降低早期进展率方面的益处
Haematologica. 2020 May;105(5):1465. doi: 10.3324/haematol.2020.246991.
2
Sustained Progression-Free Survival Benefit of Rituximab Maintenance in Patients With Follicular Lymphoma: Long-Term Results of the PRIMA Study.利妥昔单抗维持治疗滤泡性淋巴瘤患者的无进展生存获益持续存在：PRIMA 研究的长期结果。
J Clin Oncol. 2019 Nov 1;37(31):2815-2824. doi: 10.1200/JCO.19.01073. Epub 2019 Jul 24.
3
Progression-Free Survival as a Surrogate End Point for Overall Survival in First-Line Diffuse Large B-Cell Lymphoma: An Individual Patient-Level Analysis of Multiple Randomized Trials (SEAL).一线弥漫性大 B 细胞淋巴瘤中无进展生存期作为总生存期替代终点的个体患者水平分析（SEAL）。
J Clin Oncol. 2018 Sep 1;36(25):2593-2602. doi: 10.1200/JCO.2018.77.9124. Epub 2018 Jul 5.
4
A simplified scoring system in de novo follicular lymphoma treated initially with immunochemotherapy.初治滤泡性淋巴瘤采用免疫化疗治疗的简化评分系统。
Blood. 2018 Jul 5;132(1):49-58. doi: 10.1182/blood-2017-11-816405. Epub 2018 Apr 17.
5
Thirty-Month Complete Response as a Surrogate End Point in First-Line Follicular Lymphoma Therapy: An Individual Patient-Level Analysis of Multiple Randomized Trials.一线滤泡性淋巴瘤治疗中 30 个月完全缓解作为替代终点：多个随机试验的个体患者水平分析。
J Clin Oncol. 2017 Feb 10;35(5):552-560. doi: 10.1200/JCO.2016.70.8651. Epub 2016 Dec 28.
6
Early Relapse of Follicular Lymphoma After Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone Defines Patients at High Risk for Death: An Analysis From the National LymphoCare Study.利妥昔单抗联合环磷酰胺、阿霉素、长春新碱和泼尼松治疗后滤泡性淋巴瘤的早期复发预示患者死亡风险高：一项来自国家淋巴瘤关爱研究的分析
J Clin Oncol. 2015 Aug 10;33(23):2516-22. doi: 10.1200/JCO.2014.59.7534. Epub 2015 Jun 29.
7
Surrogate endpoints in clinical trials: definition and operational criteria.临床试验中的替代终点：定义与操作标准。
Stat Med. 1989 Apr;8(4):431-40. doi: 10.1002/sim.4780080407.

Early progression of disease in follicular lymphoma is a robust correlate but not a surrogate for overall survival.

作者信息

Bachy Emmanuel, Cerhan James R, Salles Gilles

机构信息

Department of Hematology, Lyon Sud Hospital, Lyon France.

Lyon 1 Claude Bernard University, Lyon, France; and.

出版信息

Blood Adv. 2021 Mar 23;5(6):1729-1732. doi: 10.1182/bloodadvances.2020003797.

DOI:10.1182/bloodadvances.2020003797
PMID:33729455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7993099/
Abstract
摘要