Melo Jéssica G A, Sousa Jossaria P, Firmino Ramon T, Matins Carolina C, Granville-Garcia Ana Flávia, Nonaka Cassiano F W, Costa Edja M M B
Postgraduate Program in Dentistry, State University of Paraíba, Campina Grande, Brazil.
Department of Dentistry, State University of Paraíba, Campina Grande, Brazil.
J Periodontal Res. 2021 Jun;56(3):443-453. doi: 10.1111/jre.12871. Epub 2021 Mar 17.
Scaling and root planning (SRP) is the gold standard for non-surgical periodontal treatment. Green tea as a supporting alternative in non-surgical periodontal treatment has been suggested as a therapeutic option in the treatment of periodontitis.
To analyse the comparative effectiveness of green tea (Camellia sinensis) in its different forms and applications for the treatment of periodontitis.
We included randomized clinical trials evaluating green tea as an adjuvant therapeutic agent to scaling and root planning (SRP) in the treatment of periodontitis. For the meta-analysis, we calculated standardized mean difference (SMD) and 95%CI comparing green tea and control (only SRP). We subgrouped by types of application forms of green tea. The certainty of the evidence was assessed through GRADE.
Nine studies were included. The follow-up time of treatments varied from 21 days to 6 months. The subgroup meta-analysis showed that the green tea as sachet reduced probing bleeding (SMD = -0.71; 95%CI) and the gingival index (SMD = -0.78; 95%CI) compared to SRP with very low certainty of evidence. The sachet (SMD = -0.29; 95%CI) and dentifrice (SMD = -1.31; 95%CI) reduced plaque index with very low certainty compared to the control. All forms of application of green tea showed very low certainty of evidence (SMD = -0.27; 95% CI) in reducing the probing depth, as well as for the loss of clinical insertion (SMD = -0.42; 95% CI) with low certainty of evidence.
There was not a difference in the effectiveness of green tea isolated or in combination with SRP to reduce probing depth. Green tea adjunct to periodontal therapy showed very low certainty of effectiveness for the treatment of periodontal disease.
龈下刮治术和根面平整术（SRP）是非手术性牙周治疗的金标准。绿茶作为非手术性牙周治疗的辅助替代方法，已被建议作为治疗牙周炎的一种治疗选择。
分析不同形式和应用的绿茶治疗牙周炎的相对疗效。
我们纳入了评估绿茶作为龈下刮治术和根面平整术（SRP）治疗牙周炎辅助治疗剂的随机临床试验。对于荟萃分析，我们计算了比较绿茶和对照组（仅SRP）的标准化均数差（SMD）和95%置信区间（CI）。我们按绿茶的应用形式类型进行了亚组分析。通过GRADE评估证据的确定性。
纳入了9项研究。治疗的随访时间从21天到6个月不等。亚组荟萃分析表明，与SRP相比，茶包形式的绿茶在降低探诊出血（SMD = -0.71；95%CI）和牙龈指数（SMD = -0.78；95%CI）方面证据确定性极低。与对照组相比，茶包（SMD = -0.29；95%CI）和牙膏（SMD = -1.31；95%CI）在降低菌斑指数方面证据确定性极低。绿茶的所有应用形式在降低探诊深度方面证据确定性都极低（SMD = -0.27；95%CI），在降低临床附着丧失方面证据确定性低（SMD = -0.42；95%CI）。
单独使用绿茶或与SRP联合使用在降低探诊深度方面效果无差异。牙周治疗中添加绿茶对治疗牙周疾病的有效性证据确定性极低。
