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长 QT 综合征变异导致患者特异性诱导多能干细胞衍生心肌细胞中 hERG1a/1b 亚基失衡。

Long QT Syndrome Variant Induces hERG1a/1b Subunit Imbalance in Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

机构信息

Cellular and Molecular Arrhythmia Research Program, Division of Cardiovascular Medicine, Department of Medicine (L.F., J.Z., G.K., E.L., C.L.A., K.M.O., L.L.E., C.T.J., T.J.K.), University of Wisconsin-Madison.

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases, China (L.F.).

出版信息

Circ Arrhythm Electrophysiol. 2021 Apr;14(4):e009343. doi: 10.1161/CIRCEP.120.009343. Epub 2021 Mar 17.

DOI:10.1161/CIRCEP.120.009343
PMID:33729832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8058932/
Abstract

[Figure: see text].

摘要

[图：见正文]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bdc/8058932/4c85b2a8845f/nihms-1684993-f0008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bdc/8058932/9aeb83251f68/nihms-1684993-f0004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bdc/8058932/4c85b2a8845f/nihms-1684993-f0008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bdc/8058932/d9b98d18b223/nihms-1684993-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bdc/8058932/e2d04c9175bc/nihms-1684993-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bdc/8058932/9aeb83251f68/nihms-1684993-f0004.jpg
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