Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otorhinolaryngology, Head and Neck Surgery (Capital Medical University), Ministry of Education, Beijing, China,
Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otorhinolaryngology, Head and Neck Surgery (Capital Medical University), Ministry of Education, Beijing, China.
ORL J Otorhinolaryngol Relat Spec. 2021;83(4):234-241. doi: 10.1159/000513528. Epub 2021 Mar 17.
Osteitis in chronic rhinosinusitis (CRS) is a predictive factor of disease severity and an important potential reason for disease recalcitrance. Other than medical treatment, transnasal endoscopic surgery could be another choice to deal with osteitis in CRS.
In this study, 2 different surgical outcomes and influence in patients with osteitis in CRS were discussed.
A retrospective analysis of 51 cases was carried out. Osteitis in CRS was confirmed by sinus computed tomography (CT). According to surgical management, patients were divided into the radical endoscopic sinus surgery (RESS) group (n = 24) and functional endoscopic sinus surgery (FESS) group (n = 27). Baseline measures and postoperative outcomes were evaluated by symptom visual analog scale (VAS), peripheral blood eosinophil percentage, serum total IgE, skin prick test, endoscopy Lund-Kennedy score, CT scan Lund-Mackay score, and global osteitis scoring scale (GOSS) in 2 groups.
There was no significant difference between the 2 groups in age, gender, and complicated with allergic rhinitis and asthma. The preoperative symptom VAS score and endoscopy Lund-Kennedy score were higher in the RESS group than in the FESS group, and the Lund-Mackay score and GOSS score were similar in the 2 groups. One year after surgery, symptom VAS scores, endoscopy Lund-Kennedy score, and Lund-Mackay score were significantly lower in the 2 groups. The endoscopy Lund-Kennedy score and Lund-Mackay score were lower in the RESS group than in the FESS group 1 year after surgery. RESS was more effective in reducing inflammatory load of sinuses in patients with osteitis in CRS.
慢性鼻-鼻窦炎(CRS)中的骨炎是疾病严重程度的预测因素,也是疾病难治的重要潜在原因。除了药物治疗,经鼻内镜手术也可能是治疗 CRS 中骨炎的另一种选择。
本研究探讨了两种不同手术方式对 CRS 中骨炎患者的治疗效果及影响。
回顾性分析了 51 例患者。通过鼻窦计算机断层扫描(CT)确认 CRS 中的骨炎。根据手术方式,患者分为根治性内镜鼻窦手术(RESS)组(n = 24)和功能性内镜鼻窦手术(FESS)组(n = 27)。通过症状视觉模拟量表(VAS)、外周血嗜酸性粒细胞百分比、血清总 IgE、皮肤点刺试验、内镜 Lund-Kennedy 评分、CT 扫描 Lund-Mackay 评分和两组的全球骨炎评分量表(GOSS)评估两组的基线指标和术后结果。
两组患者在年龄、性别、伴发变应性鼻炎和哮喘方面无显著差异。RESS 组术前症状 VAS 评分和内镜 Lund-Kennedy 评分高于 FESS 组,两组 Lund-Mackay 评分和 GOSS 评分相似。术后 1 年,两组症状 VAS 评分、内镜 Lund-Kennedy 评分和 Lund-Mackay 评分均显著降低。术后 1 年,RESS 组的内镜 Lund-Kennedy 评分和 Lund-Mackay 评分均低于 FESS 组。在减轻 CRS 中骨炎患者鼻窦炎症负荷方面,RESS 更有效。