Texas Tech University Health Science Center School of Medicine, Lubbock, Texas, USA
Texas Tech University Health Science Center School of Medicine, Lubbock, Texas, USA.
BMJ Case Rep. 2021 Mar 17;14(3):e241410. doi: 10.1136/bcr-2020-241410.
Establishing accurate symptomatology associated with novel diseases such as COVID-19 is a crucial component of early identification and screening. This case report identifies an adult patient with a history of clotting dysfunction presenting with rare cutaneous manifestations of COVID-19, known as 'COVID-19 toes'', previously described predominantly in children. Additionally, this patient presented with possible COVID-associated muscle spasticity of the lower limbs, as well as a prolonged and atypical timeline of COVID-19 infection. The rare occurrence of 'COVID-19 toes'' in this adult patient suggests that her medical history could have predisposed her to this symptom. This supports the coagulopathic hypothesis of this manifestation of COVID-19 and provides possible screening questions for patients with a similar history who might be exposed to the virus. Additionally, nervous system complaints associated with this disease are rare and understudied, so this novel symptom may also provide insight into this aspect of SARS-CoV-2.
建立与 COVID-19 等新型疾病相关的准确症状学是早期识别和筛查的关键组成部分。本病例报告确定了一名有凝血功能障碍病史的成年患者,其表现出 COVID-19 的罕见皮肤表现,即“COVID-19 脚趾”,以前主要在儿童中描述。此外,该患者还出现了可能与 COVID 相关的下肢肌肉痉挛,以及 COVID-19 感染的时间延长和非典型。这名成年患者罕见的“COVID-19 脚趾”表明她的病史可能使她易患这种症状。这支持了 COVID-19 这种表现的凝血功能障碍假说,并为可能接触过病毒且具有类似病史的患者提供了可能的筛查问题。此外,与这种疾病相关的神经系统投诉很少见且研究不足,因此这种新的症状也可能为 SARS-CoV-2 的这一方面提供深入了解。