Chaichun Amnart, Yurasakpong Laphatrada, Suwannakhan Athikhun, Iamsaard Sitthichai, Arun Supatcharee, Chaiyamoon Arada
Department of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Department of Anatomy, Faculty of Science, Mahidol University, Bangkok, Thailand.
Anat Cell Biol. 2021 Jun 30;54(2):280-284. doi: 10.5115/acb.20.323.
Porotic hyperostosis (PH) is the expansion of the cranial diploë, generating 'hair-on-end' appearance on X-rays. This condition is extremely rare and had a prevalence of 0.08%. It is alternatively known as cribra orbitalia (CO) when the orbital roof is affected. In this study, we describe the gross morphology of two skulls affected by PH and CO. The first skull belonged to a 41-year-old female previously diagnosed with beta thalassemia. The skull was affected by excessive PH and CO. The second skull, belonging to a 35-year-old male diagnosed with unspecified thalassemia, showed PH without CO. The etiology of PH and CO is discussed. In conclusion, PH and CO are extremely rare, and are of significant importance for radiologists and anatomists when interpreting radiographs or encountering unusual gross morphology of the skull.
多孔性骨质增生（PH）是颅骨板障的扩张，在X射线上产生“头发直立”的外观。这种情况极为罕见，患病率为0.08%。当眶顶受影响时，它也被称为筛孔状眶骨炎（CO）。在本研究中，我们描述了两个受PH和CO影响的颅骨的大体形态。第一个颅骨属于一名先前被诊断为β地中海贫血的41岁女性。该颅骨受到过度的PH和CO影响。第二个颅骨属于一名被诊断为未明确类型地中海贫血的35岁男性，显示有PH但无CO。文中讨论了PH和CO的病因。总之，PH和CO极为罕见，对于放射科医生和解剖学家在解读X光片或遇到颅骨异常大体形态时具有重要意义。
