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由地克珠利(Deccox)组成的饲料添加剂对育肥鸡(比利时硕腾公司)的功效。

Efficacy of the feed additive consisting of decoquinate (Deccox) for use in chickens for fattening (Zoetis Belgium SA).

作者信息

Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Durjava Mojca Fašmon, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Gropp Jürgen, Rychen Guido, Holczknecht Orsolya, Vettori Maria Vittoria

出版信息

EFSA J. 2021 Mar 8;19(3):e06453. doi: 10.2903/j.efsa.2021.6453. eCollection 2021 Mar.

Abstract

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the efficacy of decoquinate (Deccox) for chickens for fattening. In a former opinion adopted by the FEEDAP Panel, the potential of decoquinate to prevent coccidiosis in chickens for fattening could not be established due to insufficient evidence. In the present assessment, the applicant submitted new efficacy studies in chickens for fattening to address the data gaps identified in the previous opinion. In addition, the applicant proposed to increase the minimum of the dose range from 20 mg decoquinate/kg complete feed to 30 mg/kg. The coccidiostatic efficacy of decoquinate from Deccox in chickens for fattening was shown in three floor pen studies at a level of 30 mg decoquinate/kg complete feed. Considering the results of three anticoccidial sensitivity tests (ASTs) with 30 mg decoquinate/kg complete feed for chickens for fattening already described and assessed in a previous FEEDAP opinion and taking into account the newly submitted floor pen data with 30 mg decoquinate/kg complete feed, the FEEDAP Panel concludes that decoquinate from Deccox is effective in controlling coccidiosis in chickens for fattening at a minimum dose of 30 mg/kg complete feed.

摘要

应欧盟委员会的要求,动物饲料添加剂及产品或物质专家小组(FEEDAP)被要求就地克珠利(Deccox)对育肥鸡的功效提供科学意见。在FEEDAP小组先前通过的一项意见中,由于证据不足,无法确定地克珠利预防育肥鸡球虫病的潜力。在本次评估中,申请人提交了育肥鸡的新功效研究,以填补先前意见中发现的数据空白。此外,申请人提议将剂量范围的下限从每千克全价饲料20毫克地克珠利提高到30毫克/千克。在三项地面平养研究中,以每千克全价饲料30毫克地克珠利的水平显示了Deccox中的地克珠利对育肥鸡的抗球虫功效。考虑到先前FEEDAP意见中已经描述和评估的三项针对育肥鸡、每千克全价饲料含30毫克地克珠利的抗球虫敏感性试验(AST)的结果,并考虑到新提交的每千克全价饲料含30毫克地克珠利的地面平养数据,FEEDAP小组得出结论,Deccox中的地克珠利在每千克全价饲料最低剂量为30毫克时,可有效控制育肥鸡的球虫病。

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