Ehmann Sarah, Park Bernard, Chi Dennis S
Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Gynecol Oncol Rep. 2021 Feb 11;36:100713. doi: 10.1016/j.gore.2021.100713. eCollection 2021 May.
Eighty percent of women with ovarian cancer have advanced disease (FIGO stage III or IV) at the time of diagnoses and require extensive upper abdominal surgery to obtain complete gross resection (Minig et al., 2015, Eisenhauer et al., 2006). A diaphragmatic hernia is defined as abdominal contents bulging into the thoracic cavity (Spellar and Gupta, 2020). While rare following primary debulking surgery (PDS), these present with a variety of symptoms and are often misdiagnosed. Computed tomography (CT) is the diagnostic gold standard (Vertaldi et al., 2020). This video demonstrates repair of a left-sided complex diaphragm hernia via robotic video-assisted thoracic surgery in a 45-year-old with stage IVB ovarian cancer. She previously underwent extensive PDS, including modified posterior exenteration, bilateral salpingo-oophorectomy, omentectomy, bilateral pelvic lymph node dissection, appendectomy, bilateral diaphragm peritonectomy, splenectomy, resection of a right mediastinal lymph node, and insertion of a right chest tube. Complete gross resection was achieved. No left-sided diaphragm resection or repair was performed during the initial surgery. She received standard adjuvant chemotherapy with paclitaxel, carboplatin and bevacizumab. Six months postoperatively a surveillance CT scan revealed a small left hemidiaphragm hernia containing parts of the stomach. Although initially asymptomatic, she developed mild symptoms on follow-up, especially with lying supine. Imaging showed an increase in the size of the diaphragm defect. After completion of her maintenance bevacizumab therapy, corrective surgery was performed to prevent incarceration of the stomach. This video demonstrates the complex repair of this 4 × 6 cm defect located in the central tendon of the diaphragm. On two-week follow-up after corrective surgery, the patient's symptoms had resolved.
80%的卵巢癌女性在确诊时已处于晚期疾病(国际妇产科联盟[FIGO] III期或IV期),需要进行广泛的上腹部手术以实现完全肉眼切除(米尼格等人,2015年;艾森豪尔等人,2006年)。膈疝被定义为腹腔内容物突入胸腔(斯佩拉尔和古普塔,2020年)。虽然在初次肿瘤细胞减灭术(PDS)后很少见,但这些膈疝会表现出多种症状,且常被误诊。计算机断层扫描(CT)是诊断的金标准(韦尔塔尔迪等人,2020年)。本视频展示了通过机器人电视辅助胸腔镜手术对一名45岁IVB期卵巢癌患者的左侧复杂性膈疝进行修复的过程。她之前接受了广泛的PDS,包括改良后盆腔脏器清除术、双侧输卵管卵巢切除术、大网膜切除术、双侧盆腔淋巴结清扫术、阑尾切除术、双侧膈肌腹膜切除术、脾切除术、右纵隔淋巴结切除术以及右胸管置入术。实现了完全肉眼切除。初次手术期间未进行左侧膈肌切除或修复。她接受了紫杉醇、卡铂和贝伐单抗的标准辅助化疗。术后6个月,一次监测CT扫描显示一个小的左侧膈肌疝,包含部分胃。虽然最初无症状,但她在随访中出现了轻度症状,尤其是仰卧时。影像学检查显示膈肌缺损大小增加。在完成维持性贝伐单抗治疗后,进行了矫正手术以防止胃嵌顿。本视频展示了对位于膈肌中心腱的这个4×6厘米缺损的复杂修复。矫正手术后两周的随访中,患者症状已缓解。