Ehmann Sarah, Aviki Emeline M, Sonoda Yukio, Boerner Thomas, Sassine Dib, Jones David R, Park Bernard, Cohen Murray, Rosenblum Norman G, Chi Dennis S
Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Joan and Sanford I. Weill Medical College of Cornell University, New York, NY, USA.
Gynecol Oncol Rep. 2021 Mar 31;36:100759. doi: 10.1016/j.gore.2021.100759. eCollection 2021 May.
Over 80% of patients with epithelial ovarian cancer present with advanced disease, FIGO stage III or IV at the time of diagnosis. The majority require extensive upper abdominal surgery to obtain complete gross resection. This may include splenectomy, distal pancreatectomy, partial hepatectomy, cholecystectomy, and usually diaphragmatic peritonectomy or resection. Following surgery, diaphragmatic hernia-a very rare but serious complication-may occur. We describe four cases of left-sided diaphragmatic hernia resulting after debulking surgery, which included left diaphragm peritonectomy and splenectomy, in patients with advanced ovarian cancer. In association with the current shift towards more extensive debulking surgery for ovarian cancer, more patients may present with postoperative left-sided diaphragm hernia, making the prevention, diagnosis, and management of this complication important to practicing gynecologic oncologists. Intraoperatively the diaphragm should be checked thoroughly to rule out any defects, which should be closed. A diaphragmatic hernia may be easily misdiagnosed because the patient can present with various symptoms. While rare, these hernias require prompt identification, intervention and surgical correction to avoid serious complications.
超过80%的上皮性卵巢癌患者在确诊时已处于晚期疾病,国际妇产科联盟(FIGO)分期为III期或IV期。大多数患者需要进行广泛的上腹部手术以实现肉眼下完全切除。这可能包括脾切除术、胰体尾切除术、部分肝切除术、胆囊切除术,通常还包括膈腹膜切除术或切除术。手术后,膈疝——一种非常罕见但严重的并发症——可能会发生。我们描述了4例晚期卵巢癌患者在肿瘤细胞减灭术(包括左膈腹膜切除术和脾切除术)后发生左侧膈疝的病例。随着目前卵巢癌手术向更广泛的肿瘤细胞减灭术转变,可能会有更多患者出现术后左侧膈疝,因此对妇科肿瘤医生来说,预防、诊断和处理这种并发症非常重要。术中应彻底检查膈肌以排除任何缺损,如有缺损应予以闭合。膈疝可能很容易被误诊,因为患者可能出现各种症状。虽然罕见,但这些疝需要及时识别、干预和手术矫正以避免严重并发症。