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Acute Kidney Injury After High Doses of Amoxicillin.

作者信息

Mousseaux Cyril, Rafat Cédric, Letavernier Emmanuel, Frochot Vincent, Kerroumi Younes, Zeller Valérie, Luque Yosu

机构信息

Urgences Néphrologiques et Transplantation Rénale, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, France.

UMR_S1155, INSERM, Sorbonne Université, Paris, France.

出版信息

Kidney Int Rep. 2020 Dec 13;6(3):830-834. doi: 10.1016/j.ekir.2020.11.040. eCollection 2021 Mar.

DOI:10.1016/j.ekir.2020.11.040
PMID:33732998
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7938081/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aed0/7938081/04a252b79e06/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aed0/7938081/04a252b79e06/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aed0/7938081/04a252b79e06/gr1.jpg

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1
Acute Kidney Injury After High Doses of Amoxicillin.大剂量阿莫西林后的急性肾损伤
Kidney Int Rep. 2020 Dec 13;6(3):830-834. doi: 10.1016/j.ekir.2020.11.040. eCollection 2021 Mar.
2
Acute amoxicillin nephrotoxicity following an overdose.过量服用后出现急性阿莫西林肾毒性。
J Toxicol Clin Toxicol. 1986;24(2):175-82. doi: 10.3109/15563658608990456.
3
[Acute renal failure after amoxicillin crystallization].[阿莫西林结晶后急性肾衰竭]
Presse Med. 2000 Apr 8;29(13):699-701.
4
Risk of acute liver injury associated with the combination of amoxicillin and clavulanic acid.阿莫西林与克拉维酸联合使用相关的急性肝损伤风险。
Arch Intern Med. 1996 Jun 24;156(12):1327-32. doi: 10.1001/archinte.1996.00440110099013.
5
High Incidence of Amoxicillin-Induced Crystal Nephropathy in Patients Receiving High Dose of Intravenous Amoxicillin.接受大剂量静脉注射阿莫西林的患者中，阿莫西林诱导的结晶性肾病发生率较高。
J Clin Med. 2020 Jun 27;9(7):2022. doi: 10.3390/jcm9072022.
6
Dramatic Increase of Amoxicillin-Induced Crystal Nephropathy Found in a Cohort Study of French Pharmacovigilance Centers.法国药物警戒中心队列研究发现阿莫西林相关性结晶肾病急剧增加。
Antimicrob Agents Chemother. 2018 Feb 23;62(3). doi: 10.1128/AAC.01630-17. Print 2018 Mar.
7
Use of amoxicillin and amoxicillin-clavulanic acid and hospitalization for acute liver injury.阿莫西林、阿莫西林-克拉维酸的使用与急性肝损伤住院治疗
Ann Ist Super Sanita. 1999;35(3):429-33.
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Idiosyncratic hepatic toxicity in autosomal dominant polycystic kidney disease (ADPKD) patient in combined treatment with tolvaptan and amoxicillin/clavulanic acid: a case report.托伐普坦与阿莫西林/克拉维酸联合治疗常染色体显性遗传性多囊肾病（ADPKD）患者出现独特性肝毒性：病例报告。
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Amoxicillin-induced nephritis and tubulitis in a child.一名儿童的阿莫西林诱发的肾炎和肾小管炎
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Association between amoxicillin administration and outcomes in critically ill patients with acute kidney injury.阿莫西林给药与急性肾损伤重症患者预后之间的关联
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Why We May Need Higher Doses of Beta-Lactam Antibiotics: Introducing the 'Maximum Tolerable Dose'.为何我们可能需要更高剂量的β-内酰胺类抗生素：引入“最大耐受剂量”
Antibiotics (Basel). 2022 Jul 4;11(7):889. doi: 10.3390/antibiotics11070889.
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High Incidence of Acute Kidney Injury in Patients Treated with High-Dose Amoxicillin and Cloxacillin Combination Therapy.

本文引用的文献

1
High Incidence of Amoxicillin-Induced Crystal Nephropathy in Patients Receiving High Dose of Intravenous Amoxicillin.接受大剂量静脉注射阿莫西林的患者中，阿莫西林诱导的结晶性肾病发生率较高。
J Clin Med. 2020 Jun 27;9(7):2022. doi: 10.3390/jcm9072022.
2
Amoxicillin-induced crystal nephropathy: A nationwide French pharmacovigilance databases study.阿莫西林诱发的晶体性肾病：一项基于法国全国药物警戒数据库的研究
Br J Clin Pharmacol. 2020 Nov;86(11):2256-2265. doi: 10.1111/bcp.14328. Epub 2020 Jun 17.
3
Pharmacology behind Common Drug Nephrotoxicities.
大剂量阿莫西林与氯唑西林联合治疗患者急性肾损伤的高发生率
Antibiotics (Basel). 2022 Jun 4;11(6):770. doi: 10.3390/antibiotics11060770.
4
Incidence, associated factors, and effect on renal function of amoxicillin crystalluria in patients receiving high doses of intravenous amoxicillin (The CRISTAMOX Study): A cohort study.接受大剂量静脉注射阿莫西林患者中阿莫西林结晶尿的发生率、相关因素及其对肾功能的影响（CRISTAMOX研究）：一项队列研究
EClinicalMedicine. 2022 Mar 12;45:101340. doi: 10.1016/j.eclinm.2022.101340. eCollection 2022 Mar.
5
Beta-Lactams Toxicity in the Intensive Care Unit: An Underestimated Collateral Damage?重症监护病房中的β-内酰胺类药物毒性：一种被低估的附带损害？
Microorganisms. 2021 Jul 14;9(7):1505. doi: 10.3390/microorganisms9071505.
常见药物肾毒性的药理学基础。
Clin J Am Soc Nephrol. 2018 Dec 7;13(12):1897-1908. doi: 10.2215/CJN.00150118. Epub 2018 Apr 5.
4
Dramatic Increase of Amoxicillin-Induced Crystal Nephropathy Found in a Cohort Study of French Pharmacovigilance Centers.法国药物警戒中心队列研究发现阿莫西林相关性结晶肾病急剧增加。
Antimicrob Agents Chemother. 2018 Feb 23;62(3). doi: 10.1128/AAC.01630-17. Print 2018 Mar.
5
Amoxicillin dosing recommendations are very different in European countries: a cross-sectional survey.欧洲国家阿莫西林给药建议差异很大：一项横断面调查。
Clin Microbiol Infect. 2017 Jun;23(6):414-415. doi: 10.1016/j.cmi.2016.11.013. Epub 2016 Nov 23.
6
Amoxicillin Crystalluria, an Emerging Complication with an Old and Well-Known Antibiotic.阿莫西林结晶尿症，一种由一种古老且广为人知的抗生素引发的新出现的并发症。
Antimicrob Agents Chemother. 2016 Apr 22;60(5):3248. doi: 10.1128/AAC.00359-16. Print 2016 May.
7
Macroscopic amoxicillin crystalluria.肉眼可见的阿莫西林结晶尿
Lancet. 2015 Jun 6;385(9984):2296. doi: 10.1016/S0140-6736(14)62001-8. Epub 2015 Feb 11.
8
The case: a crystal-clear diagnosis: acute kidney injury in a patient with suspected meningoencephalitis. Diagnosis: Amoxicillin-induced crystal nephropathy.病例：诊断明确：一名疑似脑膜脑炎患者出现急性肾损伤。诊断结果：阿莫西林诱发的结晶性肾病。
Kidney Int. 2014 Nov;86(5):1065-6. doi: 10.1038/ki.2013.446.
9
Ampicillinuria and ampicillin crystalluria.氨苄青霉素尿症和氨苄青霉素结晶尿症。
Pediatrics. 1971 Oct;48(4):636-9.
10
Renal excretion of intravenously infused amoxycillin and ampicillin.静脉输注阿莫西林和氨苄西林后的肾脏排泄情况。
Br J Clin Pharmacol. 1985 Feb;19(2):191-201. doi: 10.1111/j.1365-2125.1985.tb02631.x.