新冠病毒病出院后的血管血栓栓塞事件：发病率及危险因素
Vascular thromboembolic events following COVID-19 hospital discharge: Incidence and risk factors.
作者信息
Eswaran Harish, Jarmul Jamie A, Shaheen Amy W, Meaux David, Long Tristan, Saccoccio Derek, Moll Stephan
机构信息
Department of Medicine University of North Carolina School of Medicine Chapel Hill NC USA.
UNC Health Chapel Hill NC USA.
出版信息
Res Pract Thromb Haemost. 2021 Feb 8;5(2):292-295. doi: 10.1002/rth2.12485. eCollection 2021 Feb.
BACKGROUND
Coronavirus disease 2019 (COVID-19) is associated with high rates of thromboembolic events in hospitalized patients. It remains to be determined if this risk persists following hospital discharge.
METHODS
We conducted a retrospective cohort study of outpatients recently hospitalized for COVID-19 to determine the incidence of vascular thromboembolic events within 30 days of discharge. We investigated the risk factors associated with these events, including intensive care admission, age, and anticoagulation.
RESULTS
Among 447 patients hospitalized for COVID-19, 2.0% experienced a vascular thromboembolic event within 30 days of discharge. No risk factor variable was significantly associated with an increased risk for these events.
CONCLUSIONS
The incidence of vascular thromboembolic events following hospital discharge for COVID-19 is low. These findings suggest against the routine use of postdischarge thromboprophylaxis in patients with COVID-19.
背景
2019年冠状病毒病（COVID-19）与住院患者的高血栓栓塞事件发生率相关。出院后这种风险是否持续仍有待确定。
方法
我们对近期因COVID-19住院的门诊患者进行了一项回顾性队列研究，以确定出院后30天内血管血栓栓塞事件的发生率。我们调查了与这些事件相关的风险因素，包括重症监护病房入住情况、年龄和抗凝情况。
结果
在447例因COVID-19住院的患者中，2.0%在出院后30天内发生了血管血栓栓塞事件。没有危险因素变量与这些事件的风险增加显著相关。
结论
COVID-19患者出院后血管血栓栓塞事件的发生率较低。这些发现不支持对COVID-19患者常规使用出院后血栓预防措施。
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