Benfield Thomas Lars, Helweg-Larsen Jannik
Ugeskr Laeger. 2021 Mar 8;183(10).
Control of the ongoing coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will require one or more vaccines. Currently, numerous SARS-CoV-2 vaccines are in either pre-clinical or clinical development. Twenty are in fase III development. In this review we summarise available safety and efficacy data of two RNA based vaccines, two non-replication competent vector-based vaccine, one inactivated whole-virus vaccine, and one subunit. All being either approved or nearing approval.
控制由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的2019冠状病毒病(COVID-19)大流行将需要一种或多种疫苗。目前,许多SARS-CoV-2疫苗正处于临床前或临床开发阶段。有20种疫苗正处于三期开发阶段。在本综述中,我们总结了两种基于RNA的疫苗、两种非复制型载体疫苗、一种灭活全病毒疫苗和一种亚单位疫苗的现有安全性和有效性数据。所有这些疫苗要么已获批,要么即将获批。