食管表皮化生：临床特征与食管鳞状上皮肿瘤风险。
Esophageal Epidermoid Metaplasia: Clinical Characteristics and Risk of Esophageal Squamous Neoplasia.
机构信息
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
出版信息
Am J Gastroenterol. 2021 Jul 1;116(7):1533-1536. doi: 10.14309/ajg.0000000000001225.
INTRODUCTION
Esophageal epidermoid metaplasia (EEM) is a rare disease.
METHODS
Patients with EEM diagnosed between 2014 and 2020 were reviewed.
RESULTS
Forty EEM cases were identified. EEM occurred in 9 (23%) patients before, concordant, or after esophageal squamous cell carcinoma (ESCC). EEM was associated with previous esophageal lichen planus in 5 patients, Barrett's esophagus 7, and esophageal adenocarcinoma 1. EEM was focal in 28 (70%) or diffuse in 12 (30%) and not detected in 45% on recent previous endoscopy.
DISCUSSION
EEM is a premalignant underrecognized condition associated with multiple conditions. Close follow-up or endoscopic treatment may be warranted because of its ESCC association.
简介
食管表皮样化生（EEM）是一种罕见疾病。
方法
回顾了 2014 年至 2020 年间诊断出的 EEM 患者。
结果
共发现 40 例 EEM 病例。9 例（23%）EEM 患者的 EEM 发生在食管鳞癌（ESCC）之前、同时或之后。5 例 EEM 与先前的食管扁平苔藓有关，7 例与 Barrett 食管有关，1 例与食管腺癌有关。28 例（70%）EEM 为局灶性，12 例（30%）为弥漫性，最近的内镜检查中 45%未发现 EEM。
讨论
EEM 是一种潜在的癌前病变，与多种疾病有关。由于与 ESCC 相关，因此需要密切随访或内镜治疗。
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