Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Cardiovasc Res. 2022 Feb 21;118(3):667-685. doi: 10.1093/cvr/cvab063.
Despite significant progress in the care of patients suffering from cardiovascular disease, there remains a persistent sex disparity in the diagnosis, management, and outcomes of these patients. These sex disparities are seen across the spectrum of cardiovascular care, but, are especially pronounced in acute cardiovascular care. The spectrum of acute cardiovascular care encompasses critically ill or tenuous patients with cardiovascular conditions that require urgent or emergent decision-making and interventions. In this narrative review, the disparities in the clinical course, management, and outcomes of six commonly encountered acute cardiovascular conditions, some with a known sex-predilection will be discussed within the basis of underlying sex differences in physiology, anatomy, and pharmacology with the goal of identifying areas where improvement in clinical approaches are needed.
尽管在心血管疾病患者的治疗方面取得了重大进展，但在这些患者的诊断、管理和结局方面仍然存在持续的性别差异。这些性别差异在心血管治疗的各个方面都存在，但在急性心血管治疗中尤为明显。急性心血管治疗的范围包括患有心血管疾病的重症或危急患者，这些患者需要紧急或紧急做出决策和干预。在这篇叙述性综述中，将根据生理学、解剖学和药理学方面的潜在性别差异，讨论六种常见的急性心血管疾病的临床过程、管理和结局方面的差异，其中一些疾病具有已知的性别倾向，目的是确定需要改进临床方法的领域。
