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两种儿科体重管理干预措施中达到临床重要减重效果的特征。

Characteristics of achieving clinically important weight loss in two paediatric weight management interventions.

机构信息

Division of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts, USA.

Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts, USA.

出版信息

Pediatr Obes. 2021 Sep;16(9):e12784. doi: 10.1111/ijpo.12784. Epub 2021 Mar 18.

DOI:10.1111/ijpo.12784
PMID:33734583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8355061/
Abstract

OBJECTIVE

To examine characteristics and lifestyle behaviours associated with achieving clinically important weight loss (CIWL) in two paediatric weight management interventions (PWMIs).

METHODS

We examined 1010 children enrolled in the STAR and Connect for Health trials. We defined achieving CIWL as any participant who had decreased their BMI z-score by ≥0.2 units over 1 year. Using log-binomial regression we examined associations of child and household characteristics and lifestyle behaviours with achieving CIWL.

RESULTS

In multivariable analyses, children with severe obesity had a lower likelihood of achieving CIWL compared to children without severe obesity (RR: 0.68 [95% CI: 0.49, 0.95]). Children who were ≥10 years were less likely to achieve CIWL (RR: 0.56 [95% CI: 0.42, 0.74]) vs those 2-6 years of age. Children who consumed <1 sugary beverage per day at the end of the intervention were more likely to achieve CIWL vs those who did not meet the goal (RR: 1.36 [95% CI 1.09-1.70]).

CONCLUSION

In this analysis of children enrolled in PWMIs, achieving CIWL was associated with younger age, not having severe obesity and consuming fewer sugary beverages at the end of the intervention. Focusing on intervening earlier in life, when a child is at a lower BMI, and reducing sugary beverages could allow for more effective PWMI's.

摘要

目的

研究两项儿科体重管理干预措施(PWMIs)中与实现临床重要减重(CIWL)相关的特征和生活方式行为。

方法

我们研究了参加 STAR 和 Connect for Health 试验的 1010 名儿童。我们将实现 CIWL 定义为任何 BMI z 评分在 1 年内降低≥0.2 单位的参与者。使用对数二项式回归,我们检查了儿童和家庭特征以及生活方式行为与实现 CIWL 的关联。

结果

在多变量分析中,与无严重肥胖的儿童相比,严重肥胖的儿童实现 CIWL 的可能性较低(RR:0.68 [95%CI:0.49, 0.95])。年龄≥10 岁的儿童比 2-6 岁的儿童更不可能实现 CIWL(RR:0.56 [95%CI:0.42, 0.74])。在干预结束时每天摄入<1 份含糖饮料的儿童比未达到目标的儿童更有可能实现 CIWL(RR:1.36 [95%CI 1.09-1.70])。

结论

在这项对参加 PWMIs 的儿童的分析中,实现 CIWL 与年龄较小、没有严重肥胖和在干预结束时摄入较少的含糖饮料有关。在儿童 BMI 较低时更早进行干预,并减少含糖饮料的摄入,可能会使 PWMI 更有效。

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