Servicio de Reumatología, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.
Department of Clinical Psychology, National Distance Education University (UNED), Madrid, Spain.
Clin Exp Rheumatol. 2021 May-Jun;39 Suppl 130(3):78-81. doi: 10.55563/clinexprheumatol/7lbz8n. Epub 2021 Mar 16.
To our knowledge, the impact of the COVID-19 pandemic on fibromyalgia (FM) patients has not been studied before. FM patients often experience clinical impairment with stress. The aim of this study was to determine whether severity of FM increases because of confinement by the COVID-19 pandemic.
This prospective study includes patients from the Combined Index of Severity of Fibromyalgia (ICAF) cohort who met the 2010 ACR FM criteria. In this cohort, all patients have a periodical evaluation of their quality of life through two questionnaires, the ICAF, which assesses the ability to perform daily living activities, anxiety and depression, and through the Patient Global Impression of Change (PGIC), which assesses overall change after a therapeutical intervention. Pre- and post-confinement measurements were analysed. Inferential statistical analysis and ANOVA for repeated measurements were used.
A total of 93 patients received a phone consultation, (95.5% females), mean (SD) age of 48.23 (8.38) years. Four patients were excluded as presenting COVID-19 and 51 (57%) completed the post-confinement ICAF. Following confinement, 25 (49%) patients got worse (group-worse) and 26 (51%) patients experienced no change or improved (group-stable). Comparisons between pre- and post-confinement ICAF did not show significant differences in both groups. Passive coping was significantly different in group-worse in pre-confinement evaluation. In the 80% of patients with passive coping predominance there were no changes in coping strategy.
No clinical impairment due to COVID-19 confinement occurred. The perceived worsening among FM patients relies primarily on how patients cope with their disease, without a real impact on clinical manifestations.
据我们所知,COVID-19 大流行对纤维肌痛(FM)患者的影响尚未被研究过。FM 患者常因压力而出现临床障碍。本研究旨在确定 COVID-19 大流行期间的禁闭是否会导致 FM 严重程度增加。
本前瞻性研究包括符合 2010 年 ACR FM 标准的综合纤维肌痛严重程度指数(ICAF)队列的患者。在该队列中,所有患者都通过 ICAF 和患者整体变化印象(PGIC)评估日常生活活动能力、焦虑和抑郁的生活质量定期进行评估,其中 PGIC 评估治疗干预后的整体变化。分析了禁闭前后的测量结果。使用推断统计分析和重复测量方差分析。
共有 93 名患者接受了电话咨询(95.5%为女性),平均(SD)年龄为 48.23(8.38)岁。由于出现 COVID-19,有 4 名患者被排除在外,有 51 名(57%)完成了禁闭后的 ICAF。禁闭后,25 名(49%)患者病情恶化(恶化组),26 名(51%)患者病情无变化或改善(稳定组)。两组之间的禁闭前后 ICAF 比较均无显著差异。在禁闭前评估中,恶化组的被动应对方式存在显著差异。在 80%以被动应对为主的患者中,应对策略没有变化。
由于 COVID-19 禁闭没有出现临床障碍。FM 患者的感知恶化主要取决于患者如何应对自己的疾病,而对临床表现没有实际影响。