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一项关于2019冠状病毒病大流行对先前诊断的纤维肌痛患者影响的横断面研究。

A Cross-Sectional Study of the Impact of the COVID-19 Pandemic on Previously Diagnosed Patients With Fibromyalgia.

作者信息

Saxena Vikas, Jakhar Kiran, Kumar Satendra, Sethi Pihu, Solanki Hariom K

机构信息

Department of Orthopedics, Government Institute of Medical Sciences, Greater Noida, IND.

Department of Psychiatry, Government Institute of Medical Sciences, Greater Noida, IND.

出版信息

Cureus. 2022 Sep 19;14(9):e29337. doi: 10.7759/cureus.29337. eCollection 2022 Sep.

Abstract

Introduction Coronavirus disease 2019 (COVID-19) was a one-of-its-kind pandemic due to its high infectivity and mortality rate. Prolonged lockdown periods imposed during the pandemic saved many lives but, on the other hand, had a huge psychological and clinical impact on patients suffering from chronic medical illnesses. Aims This study aimed to find the impact of the COVID-19 pandemic on patients with previously diagnosed fibromyalgia. Methods A prospective observational study including the cohort of previously diagnosed cases of fibromyalgia as per American College of Rheumatology (ACR) 2010 criteria where the patients were evaluated by an online survey for socio-demographic profile, subjective improvement, and objective improvement in quality of life by the Fibromyalgia Impact Questionnaire-Revised (FIQR). Pre and post-COVID-19 scores were analyzed. The statistical procedure used included the chi-square test. Results A total of 78 subjects were recruited for the study, with a female preponderance (75%) and mean (SD) age of 37.2 (9.2) years. The duration of symptoms was nine to 12 months followed by more than 12 months at the time of the first consultation for the majority of subjects. Sixty-five percent (65%) of subjects had no improvement or deterioration on FIQR. Statistical analysis This included mean, standard deviation, proportions, percentages, and the chi-square test. Conclusion COVID-19 had a significant negative impact on patients with fibromyalgia even on continued pharmacological treatment. However, there was no statistically significant data on the comparison of the overall mean score of FIQR and each domain individually with the continuation of treatment and improvement of symptoms.

摘要

引言 2019 冠状病毒病(COVID-19)因其高传染性和死亡率而成为一场独特的大流行病。疫情期间实施的长期封锁挽救了许多生命,但另一方面,对患有慢性疾病的患者产生了巨大的心理和临床影响。目的 本研究旨在探讨 COVID-19 大流行对先前诊断为纤维肌痛的患者的影响。方法 一项前瞻性观察性研究,纳入符合美国风湿病学会(ACR)2010 标准的先前诊断为纤维肌痛的病例队列,通过在线调查评估患者的社会人口学特征、主观改善情况以及使用纤维肌痛影响问卷修订版(FIQR)评估生活质量的客观改善情况。分析 COVID-19 前后的评分。所使用的统计方法包括卡方检验。结果 共招募了 78 名受试者进行研究,女性占多数(75%),平均(标准差)年龄为 37.2(9.2)岁。大多数受试者首次就诊时症状持续时间为 9 至 12 个月,其次为超过 12 个月。65%的受试者在 FIQR 上没有改善或恶化。统计分析 这包括均值、标准差、比例、百分比以及卡方检验。结论 即使继续进行药物治疗,COVID-19 对纤维肌痛患者仍有显著的负面影响。然而,关于 FIQR 的总体平均评分以及各个领域与治疗持续和症状改善情况的比较,没有统计学上显著的数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb73/9581443/166040a53122/cureus-0014-00000029337-i01.jpg

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