DiDiodato Giulio, Hassan Samah, Cooley Kieran
Department of Health Research Methods, Evidence & Impact, McMaster University Medical Centre, Hamilton, Ontario, Canada.
Centre for Education & Research, Royal Victoria Regional Health Centre, Barrie, Ontario, Canada.
PLoS One. 2021 Mar 18;16(3):e0248475. doi: 10.1371/journal.pone.0248475. eCollection 2021.
To determine acceptability of medical cannabis research in critically ill patients.
Q-methodology survey.
Convenience sample of healthcare providers and the general public were recruited at an acute care community hospital in Ontario, Canada.
In the first phase, 63 respondents provided 197 unique viewpoints in response to a topic statement about medical cannabis use in critically ill patients. Twenty-five viewpoints were selected for the q-sample. In the second phase, 99 respondents ranked these viewpoints according to an a priori quasi normal distribution ranging from +4 (most agree) to -4 (least agree). Factor analysis was combined with comments provided by survey respondents to label and describe the extracted factors.
The factor labels were hoping and caring (factor 1), pragmatic progress (factor 2), and cautious/conservative and protectionist (factor 3). Factor 1 describes a viewpoint of unequivocal support for medical cannabis research in this population with few caveats. Factor 2 describes a viewpoint of cautious support with a need to monitor for unintended adverse effects. Factor 3 describes a viewpoint of ensuring that current analgosedation techniques are optimized before exposing patients to another potentially harmful drug.
Using a q-methodology design, we were able to sample and describe the viewpoints that exist about medical cannabis research in critically ill patients. Three factors emerged that seemed to adequately describe the relative ranking of q-statements by the majority of respondents. Combining the distinguishing statements along with respondent comments allowed us to determine that the majority support medical cannabis research in critically ill patients.
确定重症患者医用大麻研究的可接受性。
Q方法调查。
在加拿大安大略省的一家急症护理社区医院招募了医疗保健提供者和普通公众的便利样本。
在第一阶段,63名受访者针对关于重症患者使用医用大麻的主题陈述提供了197个独特观点。从这些观点中选择了25个作为q样本。在第二阶段,99名受访者根据从+4(最同意)到-4(最不同意)的先验准正态分布对这些观点进行排序。将因子分析与受访者提供的评论相结合,以标记和描述提取的因子。
因子标签为希望与关怀(因子1)、务实进展(因子2)以及谨慎/保守与保护主义(因子3)。因子1描述了对该人群医用大麻研究明确支持且几乎没有限制条件的观点。因子2描述了谨慎支持并需要监测意外不良影响的观点。因子3描述了在让患者接触另一种潜在有害药物之前确保优化当前镇痛镇静技术的观点。
采用Q方法设计,我们能够对重症患者医用大麻研究的现有观点进行抽样和描述。出现了三个因子,似乎足以描述大多数受访者对q陈述的相对排序。将这些有区别的陈述与受访者的评论相结合,使我们能够确定大多数人支持重症患者的医用大麻研究。