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全球儿童早期龋病患病率:使用世界卫生组织诊断标准的系统评价和荟萃分析。

The global prevalence of early childhood caries: A systematic review with meta-analysis using the WHO diagnostic criteria.

机构信息

Department of Conservative Dentistry and Oral Health, Riga Stradins University, Riga, Latvia.

Baltic Biomaterials Centre of Excellence, Headquarters at Riga Technical University, Riga, Latvia.

出版信息

Int J Paediatr Dent. 2021 Nov;31(6):817-830. doi: 10.1111/ipd.12783. Epub 2021 Apr 30.

DOI:10.1111/ipd.12783
PMID:33735529
Abstract

AIM

To estimate the global prevalence of early childhood caries using the WHO criteria.

DESIGN

Systematic review of studies published from 1960 to 2019.

DATA SOURCES

PubMed, Google Scholar, SciELO, and LILACS. Eligibility criteria were articles using: dmft-WHO diagnostic criteria with calibrated examiners, probability sampling, and sample sizes.

STUDY SELECTION

Two reviewers searched, screened, and extracted information from the selected articles. All pooled analyses were based on random-effects models. The protocol is available on PROSPERO 2014 registration code CRD42014009578.

RESULTS

From 472 reports, 214 used WHO criteria and 125 fit the inclusion criteria. Sixty-four reports of 67 countries (published 1992-2019) had adequate data to be summarised in the meta-analysis. They covered 29 countries/59018 children. Global random-effects pooled prevalence was (percentage[95% CI]) 48[43, 53]. The prevalence by continent was Africa: 30[19, 45]; Americas: 48 [42, 54]; Asia: 52[43, 61]; Europe: 43[24, 66]; and Oceania: 82[73, 89]. Differences across countries explain 21.2% of the observed variance.

CONCLUSIONS

Early childhood caries is a global health problem, affecting almost half of preschool children. Results are reported from 29 of 195 countries. ECC prevalence varied widely, and there was more variance attributable to between-country differences rather than continent or change over time.

摘要

目的

使用世卫组织标准估计儿童早期龋的全球患病率。

设计

对 1960 年至 2019 年发表的研究进行系统综述。

数据来源

PubMed、Google Scholar、SciELO 和 LILACS。纳入标准为使用以下标准的文章:dmft-WHO 诊断标准、经过校准的检查者、概率抽样和样本量。

研究选择

两名审查员搜索、筛选并从选定的文章中提取信息。所有汇总分析均基于随机效应模型。该方案可在 PROSPERO 2014 注册编号 CRD42014009578 上查看。

结果

从 472 份报告中,有 214 份使用了世卫组织标准,125 份符合纳入标准。67 个国家的 64 份报告(发表于 1992 年至 2019 年)有足够的数据可用于荟萃分析。它们涵盖了 29 个国家/59018 名儿童。全球随机效应汇总患病率为(百分比[95%置信区间])48[43, 53]。按大洲划分的患病率为非洲:30[19, 45];美洲:48 [42, 54];亚洲:52[43, 61];欧洲:43[24, 66];大洋洲:82[73, 89]。各国之间的差异解释了观察到的方差的 21.2%。

结论

儿童早期龋是一个全球性健康问题,影响了近一半的学龄前儿童。结果来自 195 个国家中的 29 个国家。ECC 的患病率差异很大,而且由于国家之间的差异而不是大陆或随时间变化的差异导致的方差更大。

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