Children's Heart Center, Yale New Haven Children's Hospital, Yale University School of Medicine, New Haven, Connecticut, USA,
Department of Pediatrics, Section of Pediatric Critical Care, University of Arkansas for Medical Sciences and Arkansas Children's Hospital Research Institute, Little Rock, Arkansas, USA.
Cardiology. 2021;146(3):368-374. doi: 10.1159/000512777. Epub 2021 Mar 18.
Tachydysrhythmias (TDS) frequently occur after complete repair of tetralogy of Fallot (TOF). However, not much is known about the effect of TDS on morbidity and mortality after TOF repair. We sought to assess the associations between TDS and mortality and morbidity after repair of TOF using a multicentre database.
We identified all children aged 0-5 years in the Pediatric Health Information System who underwent TOF repair between 2004 and 2015. Codes for TDS were used to identify cases. Outcome variables were inpatient mortality and total length of stay (LOS). Univariate and multiple logistic and linear regression analyses were used to identify the effects of multiple risk factors, including TDS, on mortality and LOS.
A total of 7,749 patients met inclusion criteria, of which 1,493 (19%) had codes for TDS. There was no association between TDS and inpatient mortality. However, TDS were associated with 1.1 days longer LOS and accounted for 2% of the variation observed in LOS.
After complete repair of TOF, TDS were not associated with mortality and appeared to have only a modest effect on LOS.
完全修复法洛四联症（TOF）后常发生心动过速（TDS）。然而，对于 TDS 对 TOF 修复后发病率和死亡率的影响知之甚少。我们试图使用多中心数据库评估 TDS 与 TOF 修复后死亡率和发病率之间的关系。
我们在儿科健康信息系统中确定了 2004 年至 2015 年间接受 TOF 修复的所有 0-5 岁儿童。使用 TDS 代码识别病例。结果变量为住院死亡率和总住院时间（LOS）。使用单变量和多变量逻辑回归和线性回归分析来确定包括 TDS 在内的多个危险因素对死亡率和 LOS 的影响。
共有 7749 名患者符合纳入标准，其中 1493 名（19%）有 TDS 代码。TDS 与住院死亡率之间没有关联。然而，TDS 与 LOS 延长 1.1 天有关，占 LOS 观察到的变异的 2%。
在 TOF 完全修复后，TDS 与死亡率无关，似乎对 LOS 只有适度的影响。
