Kitsiou Alkisti, Zuhorn Frédéric, Wachter Rolf, Israel Carsten Walter, Schäbitz Wolf-Rüdiger, Rogalewski Andreas
Evangelisches Klinikum Bethel, Klinik für Neurologie, Bielefeld, Deutschland.
Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Leipzig, Deutschland.
Dtsch Med Wochenschr. 2021 Mar;146(6):403-409. doi: 10.1055/a-1309-8701. Epub 2021 Mar 18.
Embolic stroke of undetermined source (ESUS) represents a subpopulation of cryptogenic strokes defined by its embolic stroke pattern on imaging and if after a carefully performed diagnostic evaluation, a specific, well recognized cause of stroke has not been identified. This review article analyses the basics of the ESUS concept and provides an overview of the evidence from recent cohort studies. The definition, aetiology and diagnosis of ESUS are reassessed. Targeted diagnostics in ESUS patients can reduce the number of cryptogenic strokes by making a specific diagnosis.
不明来源栓塞性卒中(ESUS)是隐源性卒中的一个亚组,其定义基于影像学上的栓塞性卒中模式,且在经过仔细的诊断评估后,未发现特定的、公认的卒中病因。这篇综述文章分析了ESUS概念的基础,并概述了近期队列研究的证据。对ESUS的定义、病因和诊断进行了重新评估。对ESUS患者进行针对性诊断可以通过做出特定诊断来减少隐源性卒中的数量。