Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Environmental Health Engineering, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Environmental Health Engineering, School of Health, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran; Health Sciences Research Center, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran; Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Sci Total Environ. 2021 Jun 1;771:144882. doi: 10.1016/j.scitotenv.2020.144882. Epub 2021 Jan 29.
Suicide is a major public health problem, with some environmental risk factors.
This meta-analysis study explored the association between short-term exposure to air pollution and suicide mortality, with an emphasis on different lag times.
A systematic search was used to find relevant studies in databases including Scopus, Web of Knowledge, Pubmed, and Embase published up to 19 May 2020. The inclusion criteria included case-crossover or time-series studies assessing the association of criteria air pollutants with suicide mortality at different Lag Days of 0-7 (LD0 to LD7) and Cumulative Lags of 1-7 days (CL1 to CL7). Odds ratios (OR) were calculated with 95% confidence intervals (CI).
Of 1436 retrieved articles, 11 were eligible for data extraction, representing data on 283,550 suicides published between 2010 and 2019. The odds of suicide death increase with each 10 μg/m increase in the mean concentrations of NO at CL1 (1.013: 1.006-1.021), CL2 (1.028: 1.003-1.053), CL3 (1.035: 1.001-1.070), and LD2 (1.011: 1.001-1.022), SO at CL1 (1.024: 1.014-1.034), CL2 (1.030: 1.012-1.048), CL3 (1.029: 1.009-1.049), and CL4 (1.027: 1.005-1.049), O at CL6 (1.008: 1.000-1.016), PM at CL1 (1.004: 1.000-1.008), and PM at CL1 (1.017: 1.003-1.031). Besides, the odds of suicide death increases with each 0.5 mg/m increase in the mean concentration of CO at LD6 (1.005: 1.000-1.011). However, it decreased with increased O exposure at LD3 (0.997: 0.994-1.000).
The study supports a positive association between air pollution and suicide mortality. No immediate risk was elucidated but the possible effects seem to be exerted cumulatively.
自杀是一个主要的公共卫生问题，存在一些环境风险因素。
本荟萃分析研究探讨了短期暴露于空气污染与自杀死亡率之间的关系，重点关注不同的时间滞后。
系统检索了 Scopus、Web of Knowledge、Pubmed 和 Embase 数据库中截至 2020 年 5 月 19 日发表的相关研究。纳入标准包括病例交叉或时间序列研究，评估了不同滞后时间（0-7 天[LD0 至 LD7]和 1-7 天[CL1 至 CL7]的累积滞后时间）的标准空气污染物与自杀死亡率之间的关联。使用 95%置信区间（CI）计算比值比（OR）。
在检索到的 1436 篇文章中，有 11 篇符合数据提取标准，这些文章代表了 2010 年至 2019 年期间发表的关于 283550 例自杀事件的数据。随着 NO 在 CL1（1.013：1.006-1.021）、CL2（1.028：1.003-1.053）、CL3（1.035：1.001-1.070）和 LD2（1.011：1.001-1.022）、SO 在 CL1（1.024：1.014-1.034）、CL2（1.030：1.012-1.048）、CL3（1.029：1.009-1.049）和 CL4（1.027：1.005-1.049）的平均浓度每增加 10μg/m，自杀死亡的几率增加；O 在 CL6（1.008：1.000-1.016）、PM 在 CL1（1.004：1.000-1.008）和 PM 在 CL1（1.017：1.003-1.031）的平均浓度每增加 0.5mg/m，自杀死亡的几率也会增加。此外，CO 在 LD6（1.005：1.000-1.011）的平均浓度每增加 0.5mg/m，自杀死亡的几率增加。然而，在 LD3 时，随着 O 暴露的增加，自杀死亡率下降（0.997：0.994-1.000）。
该研究支持空气污染与自杀死亡率之间存在正相关关系。虽然没有发现即时风险，但可能存在累积效应。
