Stewart R J, Lawson A H, Weaver J P
Section of Urology, University of Dundee, Scotland, United Kingdom.
J Urol. 1988 Jun;139(6):1355-8. doi: 10.1016/s0022-5347(17)42918-1.
Electron microscopy studies of the ultrastructure of bladder carcinoma treated by intravesical instillation of ethoglucid and mitomycin are described. Ethoglucid acts mainly by disrupting cells' intercellular bonds. Mitomycin acts on the cell nucleus. It is suggested that these differences in action form a basis for sequential therapy.
本文描述了通过膀胱内灌注乙环氧丙烷和丝裂霉素治疗膀胱癌的超微结构的电子显微镜研究。乙环氧丙烷主要通过破坏细胞间连接起作用。丝裂霉素作用于细胞核。有人认为这些作用差异构成了序贯治疗的基础。