School of Public Health, Sun Yat-Sen University, Guangzhou, China.
Division of Behavioral Health and Health Promotion, The School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Epidemiol Psychiatr Sci. 2021 Mar 19;30:e24. doi: 10.1017/S2045796021000081.
There is a lack of mental health promotion and treatment services targeting HIV-positive men who have sex with men (HIVMSM) in China. The aim of this study was to evaluate the mental health promotion efficacy of an online intervention that combined Three Good Things (TGT) with electronic social networking (TGT-SN) and an intervention that used TGT only (TGT-only), compared with a control group.
We conducted a randomised controlled trial among HIVMSM in Chengdu, China. The participants were randomly assigned to the TGT-SN, TGT-only, and control groups. The participants in the TGT-SN group were divided into five social network groups and asked to post brief messages to the group about three good things that they had experienced and for which they felt grateful. The participants in the TGT-only group were only required to write down their three good things daily without sharing them with others. The control group received information about mental health promotion once a week for a month. The primary outcome was probable depression. Secondary outcomes were anxiety, positive and negative affect, gratitude, happiness and social support. These outcomes were assessed at baseline, 1, 3, 6 and 12 months after the intervention. Repeated-measures analyses were conducted using generalised estimation equations. The study was registered with the Chinese Clinical Trial Registry (ChiCTR-TRC-13003252).
Between June 2013 and May 2015, 404 participants were enrolled and randomly assigned to either the TGT-SN (n = 129), TGT-only (n = 139) or control group (n = 136). The main effects of TGT-SN (adjusted odds ratio (aOR) = 0.75, 95% CI 0.52-1.09; p = 0.131) and TGT-only (aOR = 0.83, 95% CI 0.57-1.21; p = 0.332) in reducing depression were statistically non-significant. The participants of the TGT-SN group showed significantly lower anxiety symptoms (aOR = 0.62, 95% CI 0.43-0.89; p = 0.009) and negative affect (β = -1.62, 95% CI 2.98 to -0.26; p = 0.019) over time compared with those of the control group. No significant main effect was found for any secondary outcomes for the TGT-only group.
The novel intervention combining the TGT exercise with electronic social networking was found effective in reducing anxiety and negative affect among HIVMSM.
中国针对 HIV 阳性男男性行为者（HIVMSM）的心理健康促进和治疗服务匮乏。本研究旨在评估一种将三件好事（TGT）与电子社交网络（TGT-SN）相结合的在线干预措施与仅使用 TGT（TGT-only）的干预措施的心理健康促进效果，并与对照组进行比较。
我们在中国成都对 HIVMSM 进行了一项随机对照试验。参与者被随机分配到 TGT-SN、TGT-only 和对照组。TGT-SN 组的参与者被分为五个社交网络小组，并被要求向小组发布简短的信息，说明他们经历过的三件好事，并对此表示感激。TGT-only 组的参与者只需每天写下他们的三件好事，而无需与他人分享。对照组每月接受一次心理健康促进信息。主要结果是可能的抑郁。次要结果是焦虑、积极和消极情绪、感激、幸福和社会支持。这些结果在干预前、1、3、6 和 12 个月进行评估。使用广义估计方程进行重复测量分析。该研究在中国临床试验注册中心（ChiCTR-TRC-13003252）注册。
2013 年 6 月至 2015 年 5 月期间，共纳入 404 名参与者，并随机分配至 TGT-SN 组（n=129）、TGT-only 组（n=139）或对照组（n=136）。TGT-SN（调整优势比（aOR）=0.75，95%置信区间 0.52-1.09；p=0.131）和 TGT-only（aOR=0.83，95%置信区间 0.57-1.21；p=0.332）在降低抑郁方面的主要效果无统计学意义。与对照组相比，TGT-SN 组的参与者焦虑症状（aOR=0.62，95%置信区间 0.43-0.89；p=0.009）和负性情绪（β=-1.62，95%置信区间 2.98 至-0.26；p=0.019）随时间显著降低。TGT-only 组在任何次要结果方面均未发现显著的主要效果。
将 TGT 练习与电子社交网络相结合的新干预措施可有效降低 HIVMSM 的焦虑和负性情绪。
