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新型内镜下治疗胃黏膜下小肿瘤:单中心经验(附视频)。

Novel endoscopic management for small gastric submucosal tumors: A single-center experience (with video).

机构信息

Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.

Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.

出版信息

Dig Liver Dis. 2021 Jul;53(7):895-899. doi: 10.1016/j.dld.2021.02.014. Epub 2021 Mar 16.

Abstract

BACKGROUND AND AIMS

To explore the novel treatment of small gastric submucosal tumors (SMTs) originating from the muscularis propria layer (SMT-MPs), we utilized endoscopic band ligation (EBL) with a precut of the covering mucosa.

METHODS

From Jan. 2012 to Dec. 2019, 111 patients with 124 gastric SMT-MPs were treated by precutting EBL. The clinical characteristics, operation duration, postoperative adverse events, and follow-up profiles were retrospectively collected.

RESULTS

A total of 124 tumors from 111 patients were successfully treated by precutting EBL. No adverse events, including perforation and major bleeding, were observed. Furthermore, 93 patients (83.8%) underwent endoscopic surveillance postoperatively, and during the follow-up period, no local recurrence was detected.

CONCLUSIONS

Precutting EBL appears to be a safe and simple method for removing gastric SMT-MPs < 16 mm (mainly indicated for potentially malignant GISTs), but further studies with longer follow-up are needed to assess the radicality of this intervention.

摘要

背景与目的

为探索固有肌层起源的小胃黏膜下肿瘤(SMT)的新型治疗方法,我们采用了黏膜预切开的内镜套扎术(EBL)。

方法

回顾性收集了 2012 年 1 月至 2019 年 12 月期间 111 例共 124 个胃固有肌层 SMT 患者的临床特征、手术时间、术后不良事件和随访资料。

结果

124 个肿瘤均采用黏膜预切开 EBL 成功治疗,未出现穿孔和大出血等不良事件。93 例(83.8%)患者术后进行了内镜监测,随访期间未发现局部复发。

结论

黏膜预切开 EBL 似乎是一种安全、简单的方法,适用于直径<16mm 的胃固有肌层 SMT(主要针对潜在恶性 GISTs),但需要进一步进行长期随访研究以评估该干预的根治性。

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