Pearce Jasmine, Sheridan Ray, Shaw Johnathan, Senior Thomas
Department of General Medicine, Royal Devon and Exeter Hospital, Exeter, UK
Department of Healthcare for Older People, Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, UK.
BMJ Case Rep. 2021 Mar 18;14(3):e237456. doi: 10.1136/bcr-2020-237456.
This case demonstrates an atypical radiological presentation of cerebral toxoplasmosis in a 62-year-old HIV-positive patient. The diagnosis is discussed alongside MRI imaging, laboratory results and treatment. Central nervous system toxoplasmosis is typically associated with ring enhancing lesions on neuroimaging with contrast, but the radiology for this patient shows diffuse white matter changes and ependymal enhancement, which would normally suggest an alternative diagnosis.
该病例展示了一名62岁HIV阳性患者脑弓形虫病的非典型影像学表现。结合MRI影像、实验室检查结果及治疗情况对诊断进行了讨论。中枢神经系统弓形虫病在神经影像学检查中通常表现为有强化的环形病灶,但该患者的影像学检查显示弥漫性白质改变和室管膜强化,而这通常提示其他诊断。