National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Pittsburgh, Pennsylvania, USA
Health and Human Development, University of Pittsburgh School of Education, Pittsburgh, Pennsylvania, USA.
Occup Environ Med. 2021 Oct;78(10):724-730. doi: 10.1136/oemed-2020-106948. Epub 2021 Mar 18.
Emerging evidence, predominately from European and Asian countries, describes opposing effects of occupational physical activity (OPA) and leisure-time physical activity (LTPA) on cardiovascular health. This analysis examined cardiovascular disease (CVD) prevalence associated with OPA and LTPA.
This cross-sectional analysis of 2015 National Health Interview Survey data (n=16 974) employed logistic regression to estimate odds (OR) of self-reported CVD (coronary heart disease, heart attack, stroke or angina) with self-reported total occupational activity (TOA), occupational exertion (OE), occupational standing and walking (OSW) and LTPA. OPA was measured using two questions: 'How often does your job involve…' (1) 'repeated lifting, pushing, pulling or bending?' (OE) and (2) 'standing or walking around?' (OSW) with responses on a 5-item Likert scale (0=never, 4=always). TOA was categorised similarly after summing OE and OSW scores. LTPA was defined as 0, 1-149 or ≥150 min/week of moderate-to-vigorous activity. All models adjusted for common socioeconomic variables and additional analyses were stratified by sex, smoking status and LTPA.
Odds for CVD were higher when 'always' performing TOA (OR 1.99 95% CI 1.12 to 3.53), OE (OR 2.15, 95% CI 1.45 to 3.19) or OSW (OR 1.84, 95% CI 1.07 to 3.17) compared with 'never'. When restricting to never-smokers, odds for CVD were higher when 'always' performing TOA (OR 3.00, 95% CI 1.38 to 6.51) and OE (OR 3.00, 95% CI 1.80 to 5.02) versus 'never'.
Associations of high OPA with CVD were equally apparent across sexes, stronger in lower LTPA levels and stronger in never-smokers. While uncontrolled confounding is still possible, even after extensive adjustment, the seemingly paradoxical adverse associations with OPA and CVD should be investigated further.
越来越多的证据表明,职业体力活动(OPA)和休闲时间体力活动(LTPA)对心血管健康的影响可能相反,这些证据主要来自欧洲和亚洲国家。本分析旨在探讨与 OPA 和 LTPA 相关的心血管疾病(CVD)患病率。
本研究采用 2015 年全国健康访谈调查(n=16974)的横断面数据分析,采用逻辑回归估计自我报告 CVD(冠心病、心脏病发作、中风或心绞痛)与自我报告总职业活动(TOA)、职业用力(OE)、职业站立和走动(OSW)和 LTPA 的比值比(OR)。OPA 通过两个问题来衡量:“您的工作……”(1)“经常重复举起、推动、拉动或弯曲?”(OE)和(2)“站立或走动?”(OSW),答案为 5 分制(0=从不,4=总是)。TOA 是通过 OE 和 OSW 得分相加后分类的。LTPA 定义为每周中等到剧烈活动 0、1-149 或≥150 分钟。所有模型均调整了常见的社会经济变量,并且进一步按性别、吸烟状况和 LTPA 进行分层分析。
与“从不”相比,“总是”进行 TOA(OR 1.99,95%CI 1.12 至 3.53)、OE(OR 2.15,95%CI 1.45 至 3.19)或 OSW(OR 1.84,95%CI 1.07 至 3.17)时,CVD 的几率更高。在从不吸烟者中,与“从不”相比,“总是”进行 TOA(OR 3.00,95%CI 1.38 至 6.51)和 OE(OR 3.00,95%CI 1.80 至 5.02)时,CVD 的几率更高。
OPA 与 CVD 之间的关联在性别之间同样明显,在低水平的 LTPA 下更强,在从不吸烟者中更强。尽管经过广泛调整后仍可能存在未控制的混杂因素,但 OPA 与 CVD 之间似乎存在矛盾的不良关联,应进一步研究。