Burkadze Eka, Axobadze Ketevan, Chkhaberidze Nino, Chikhladze Nino, Coman Madalina Adina, Dulf Diana, Peek-Asa Corinne
Department of Public Health, Faculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia.
Department of Public Health, College of Political, Administrative and Communication Sciences, Babes-Bolyai University, Cluj-Napoca, Romania.
Risk Manag Healthc Policy. 2021 Mar 12;14:1041-1051. doi: 10.2147/RMHP.S290175. eCollection 2021.
Traumatic brain injury (TBI) is one of the major causes of morbidity and mortality worldwide, disproportionally affecting low- and middle-income countries (LMICs). Epidemiological characteristics of TBI at a national level are absent for most LMICs including Georgia. This study aimed to establish the registries and assess causes and outcomes in TBI patients presenting to two major trauma hospitals in the capital city -Tbilisi.
The prospective observational study was conducted at Acad. O. Gudushauri National Medical Center and M. Iashvili Children's Central Hospital from March, 1 through August, 31, 2019. Patients of all age groups admitted to one of the study hospitals with a TBI diagnosis were eligible for participation. Collected data were uploaded using the electronic data collection tool -REDCap, analyzed through SPSS software and evaluated to provide detailed information on TBI-related variables and outcomes using descriptive statistics.
Overall, 542 hospitalized patients were enrolled during the study period, about 63% were male and the average age was 17.7. The main causes of TBI were falls (58%) and struck by or against an object (22%). The 97% suffered from mild TBI (GCS 13-15). Over 23% of patients arrived at the hospital more than 1 hour after injury and 25% after more than 4-hours post-injury. Moderate and severe TBI were associated with an increased hospital length of stay. Mortality rate of severe TBI was 54%.
This study provides important information on the major epidemiological characteristics of TBI in Georgia, which should be considered for setting priorities for injury management.
创伤性脑损伤（TBI）是全球发病和死亡的主要原因之一，对低收入和中等收入国家（LMICs）的影响尤为严重。包括格鲁吉亚在内的大多数LMICs缺乏国家层面的TBI流行病学特征。本研究旨在建立登记系统，并评估前往首都第比利斯两家主要创伤医院就诊的TBI患者的病因和预后。
前瞻性观察性研究于2019年3月1日至8月31日在阿卡德·奥·古杜沙里国立医学中心和M. 伊阿什维利儿童中央医院进行。入住其中一家研究医院且被诊断为TBI的所有年龄组患者均符合参与条件。收集的数据使用电子数据收集工具REDCap上传，通过SPSS软件进行分析，并使用描述性统计评估以提供有关TBI相关变量和预后的详细信息。
总体而言，研究期间共纳入542例住院患者，约63%为男性，平均年龄为17.7岁。TBI的主要原因是跌倒（58%）和被物体撞击（22%）。97%的患者患有轻度TBI（格拉斯哥昏迷量表评分13 - 15分）。超过23%的患者在受伤后1小时以上到达医院，25%的患者在受伤后4小时以上到达医院。中度和重度TBI与住院时间延长相关。重度TBI的死亡率为54%。
本研究提供了格鲁吉亚TBI主要流行病学特征的重要信息，在确定损伤管理的优先事项时应予以考虑。
